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Klf16 Gene Detail
Summary
  • Symbol
    Klf16
  • Name
    Kruppel-like transcription factor 16
  • Synonyms
    BTEB4, DRRF
  • Feature Type
    protein coding gene
  • IDs
    MGI:2153049
    NCBI Gene: 118445
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:80402955-80413130 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    217 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2153049
 protein coding gene Chr10:80402955-80413155 (-)
129S1/SvImJ ENSMUSG00200049168
 protein coding gene Chr10:77028967-77039158 (-)
A/J ENSMUSG00195048415
 protein coding gene Chr10:77424536-77434727 (-)
AKR/J ENSMUSG00220046334
 protein coding gene Chr10:77022209-77032399 (-)
BALB/cJ ENSMUSG00180051794
 protein coding gene Chr10:77434987-77445180 (-)
C3H/HeJ ENSMUSG00175048919
 protein coding gene Chr10:77305765-77315956 (-)
C57BL/6NJ ENSMUSG00215050854
 protein coding gene Chr10:77047566-77057763 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015590
 protein coding gene Chr10:74562532-74572892 (-)
CAST/EiJ ENSTCUG00005049448
 protein coding gene Chr10:76933505-76943728 (-)
CBA/J ENSMUSG00210044100
 protein coding gene Chr10:77161804-77171996 (-)
DBA/2J ENSMUSG00185053152
 protein coding gene Chr10:77504219-77514410 (-)
FVB/NJ ENSMUSG00205050128
 protein coding gene Chr10:77216986-77227179 (-)
JF1/MsJ ENSUMUG00000051619
 protein coding gene Chr10:78736353-78746579 (-)
LP/J ENSMUSG00230049647
 protein coding gene Chr10:79273845-79284036 (-)
NOD/ShiLtJ ENSMUSG00190048879
 protein coding gene Chr10:77417954-77428143 (-)
NZO/HlLtJ ENSMUSG00225050139
 protein coding gene Chr10:83560358-83570549 (-)
PWK/PhJ ENSLUMG00010048027
 protein coding gene Chr10:77097586-77107782 (-)
SPRET/EiJ ENSMSPG00010041841
 protein coding gene Chr10:78712963-78723144 (-)
WSB/EiJ ENSIUOG00005043423
 protein coding gene Chr10:77121932-77132121 (-)



Homology
more
  • Human Ortholog
    KLF16, KLF transcription factor 16
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KLF16, KLF transcription factor 16
  • Synonyms
    BTEB4, DRRF, NSLP2
  • Links
    NCBI Gene ID: 83855
    UniProt: Q9BXK1

  • Chr Location
    19p13.3; chr19:1852399-1876536 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    715
  • Tissues
    100
  • cDNA Data
    27
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 118445 NCBI Gene Model | MGI Sequence Detail 10176 C57BL/6J ±  kb
    transcript NM_078477 RefSeq | MGI Sequence Detail 2652 C57BL/6  
    polypeptide P58334 UniProt | EBI | MGI Sequence Detail 251 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 29
      cDNA 27
      Primer pair 2
      Antibodies 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2143679
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 5
      Gene Ontology 6
      Phenotypes 14
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory