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Depdc1b Gene Detail
Summary
  • Symbol
    Depdc1b
  • Name
    DEP domain containing 1B
  • Synonyms
    XTP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145425
    NCBI Gene: 218581
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:108452592-108526100 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 59.69 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2788 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2145425
 protein coding gene Chr13:108452592-108544316 (+)
129S1/SvImJ ENSMUSG00200029940
 protein coding gene Chr13:102895223-102987167 (+)
A/J ENSMUSG00195012608
 protein coding gene Chr13:103457612-103542634 (+)
AKR/J ENSMUSG00220029523
 protein coding gene Chr13:101875333-101970201 (+)
BALB/cJ ENSMUSG00180027915
 protein coding gene Chr13:104036054-104121069 (+)
C3H/HeJ ENSMUSG00175025321
 protein coding gene Chr13:104134156-104219175 (+)
C57BL/6NJ ENSMUSG00215021250
 protein coding gene Chr13:104102108-104193564 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018880
 protein coding gene Chr13:101732711-101818660 (+)
CAST/EiJ ENSTCUG00005024107
 protein coding gene Chr13:103211994-103297807 (+)
CBA/J ENSMUSG00210010442
 protein coding gene Chr13:103459672-103544682 (+)
DBA/2J ENSMUSG00185025671
 protein coding gene Chr13:107215108-107300125 (+)
FVB/NJ ENSMUSG00205006761
 protein coding gene Chr13:102880419-102965451 (+)
JF1/MsJ ENSUMUG00000011578
 protein coding gene Chr13:106729801-106815462 (+)
LP/J ENSMUSG00230006064
 protein coding gene Chr13:117362598-117454547 (+)
NOD/ShiLtJ ENSMUSG00190018076
 protein coding gene Chr13:103766616-103858074 (+)
NZO/HlLtJ ENSMUSG00225037107
 protein coding gene Chr13:109644928-109749656 (+)
PWK/PhJ ENSLUMG00010009616
 protein coding gene Chr13:102762949-102847232 (+)
SPRET/EiJ ENSMSPG00010016521
 protein coding gene Chr13:104377924-104451776 (+)
WSB/EiJ ENSIUOG00005008225
 protein coding gene Chr13:102905601-103004368 (+)



Homology
more
  • Human Ortholog
    DEPDC1B, DEP domain containing 1B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DEPDC1B, DEP domain containing 1B
  • Synonyms
    BRCC3, XTP1
  • Links
    NCBI Gene ID: 55789
    UniProt: Q8WUY9

  • Chr Location
    5q12.1; chr5:60596912-60700194 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    602
  • Tissues
    5
  • cDNA Data
    20
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 218581 NCBI Gene Model | MGI Sequence Detail 73509 C57BL/6J ±  kb
transcript NM_178683 RefSeq | MGI Sequence Detail 2493 C57BL/6  
polypeptide Q8BH88 UniProt | EBI | MGI Sequence Detail 529 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 20

    Microarray probesets 2
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
  • Latest
    J:294003 Figeac N, et al., DEPDC1B is a key regulator of myoblast proliferation in mouse and man. Cell Prolif. 2020 Jan;53(1):e12717
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory