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Lhfpl2 Gene Detail
Summary
  • Symbol
    Lhfpl2
  • Name
    lipoma HMGIC fusion partner-like 2
  • Synonyms
    mKIAA0206, vgim
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145236
    NCBI Gene: 218454
  • Alliance
    genome feature page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:94194304-94331917 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 49.03 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4447 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2145236
 protein coding gene Chr13:94193659-94331918 (+)
129S1/SvImJ ENSMUSG00200007882
 protein coding gene Chr13:88695915-88833552 (+)
A/J ENSMUSG00195023858
 protein coding gene Chr13:89197114-89334392 (+)
AKR/J ENSMUSG00220013448
 protein coding gene Chr13:87651982-87789627 (+)
BALB/cJ ENSMUSG00180015856
 protein coding gene Chr13:89732315-89869958 (+)
C3H/HeJ ENSMUSG00175022213
 protein coding gene Chr13:89896158-90033791 (+)
C57BL/6NJ ENSMUSG00215002931
 protein coding gene Chr13:89793788-89931421 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018786
 protein coding gene Chr13:87730603-87869599 (+)
CAST/EiJ ENSTCUG00005009141
 protein coding gene Chr13:88983692-89121474 (+)
CBA/J ENSMUSG00210024107
 protein coding gene Chr13:89217869-89355510 (+)
DBA/2J ENSMUSG00185016915
 protein coding gene Chr13:92878577-93016209 (+)
FVB/NJ ENSMUSG00205007357
 protein coding gene Chr13:88682814-88820440 (+)
JF1/MsJ ENSUMUG00000015566
 protein coding gene Chr13:92554198-92693077 (+)
LP/J ENSMUSG00230032644
 protein coding gene Chr13:102896569-103034185 (+)
NOD/ShiLtJ ENSMUSG00190017419
 protein coding gene Chr13:89576196-89713841 (+)
NZO/HlLtJ ENSMUSG00225033119
 protein coding gene Chr13:95410229-95547859 (+)
PWK/PhJ ENSLUMG00010011123
 protein coding gene Chr13:88664300-88811783 (+)
SPRET/EiJ ENSMSPG00010006666
 protein coding gene Chr13:90027110-90048666 (+)
WSB/EiJ ENSIUOG00005029500
 protein coding gene Chr13:88589502-88727522 (+)



Homology
more
  • Human Ortholog
    LHFPL2, LHFPL tetraspan subfamily member 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LHFPL2, LHFPL tetraspan subfamily member 2
  • Links
    NCBI Gene ID: 10184
    UniProt: Q6ZUX7

  • Chr Location
    5q14.1; chr5:78485215-78770021 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    22 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Females homozygous for a spontaneous point mutation have a completely closed vagina, soft swelling of the perineum and buildup of viscous fluid in the uteri.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    622
  • Tissues
    20
  • cDNA Data
    14
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000045312 Ensembl Gene Model | MGI Sequence Detail 137614 C57BL/6J ±  kb
    transcript ENSMUST00000118195 Ensembl | MGI Sequence Detail 3611 Not Applicable  
    polypeptide ENSMUSP00000112655 Ensembl | MGI Sequence Detail 222 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 15
      Primer pair 2
      Antibodies 1

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:2145409, MGI:4837107
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 3
      Gene Ontology 3
      Phenotypes 15
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory