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Rprml Gene Detail
Summary
  • Symbol
    Rprml
  • Name
    reprimo-like
  • Feature Type
    protein coding gene
  • IDs
    MGI:2144486
    NCBI Gene: 104582
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:103540396-103541405 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 67.41 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    92 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2144486
protein coding gene Chr11:103540335-103541406 (+)
129S1/SvImJ ENSMUSG00200051478
protein coding gene Chr11:100827505-100828514 (+)
A/J ENSMUSG00195050046
protein coding gene Chr11:100526366-100527376 (+)
AKR/J ENSMUSG00220048237
protein coding gene Chr11:100740498-100741507 (+)
BALB/cJ ENSMUSG00180051801
protein coding gene Chr11:100860702-100861711 (+)
C3H/HeJ ENSMUSG00175040164
protein coding gene Chr11:100801098-100802107 (+)
C57BL/6NJ ENSMUSG00215053446
protein coding gene Chr11:100363157-100364166 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017283
protein coding gene Chr11:99622080-99623087 (+)
CAST/EiJ ENSTCUG00005048330
protein coding gene Chr11:100293291-100294300 (+)
CBA/J ENSMUSG00210051736
protein coding gene Chr11:100502145-100503155 (+)
DBA/2J ENSMUSG00185049638
protein coding gene Chr11:100850870-100851879 (+)
FVB/NJ ENSMUSG00205039499
protein coding gene Chr11:100674864-100675873 (+)
JF1/MsJ ENSUMUG00000020041
protein coding gene Chr11:101109225-101110232 (+)
LP/J ENSMUSG00230034691
protein coding gene Chr11:101903256-101904265 (+)
NOD/ShiLtJ ENSMUSG00190049325
protein coding gene Chr11:100868856-100869865 (+)
NZO/HlLtJ ENSMUSG00225049854
protein coding gene Chr11:103923364-103924373 (+)
PWK/PhJ ENSLUMG00010041655
protein coding gene Chr11:100650478-100651485 (+)
SPRET/EiJ ENSMSPG00010050333
protein coding gene Chr11:101125434-101126439 (+)
WSB/EiJ ENSIUOG00005048692
protein coding gene Chr11:100644255-100645265 (+)



Homology
more
  • Human Ortholog
    RPRML, reprimo like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPRML, reprimo like
  • Links
    NCBI Gene ID: 388394
    UniProt: Q8N4K4

  • Chr Location
    17q21.32; chr17:46978156-46979253 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000046215 Ensembl Gene Model | MGI Sequence Detail 1010 C57BL/6J ±  kb
    transcript ENSMUST00000057870 Ensembl | MGI Sequence Detail 1010 Not Applicable  
    polypeptide ENSMUSP00000053993 Ensembl | MGI Sequence Detail 117 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 8

      Microarray probesets 2
    References
    more
    • Summaries
      All 28
      Developmental Gene Expression 2
      Gene Ontology 1
      Phenotypes 9
    • Earliest
      J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
    • Latest
      J:364972 Hara Y, et al., The spatial transcriptome of the late-stage embryonic and postnatal mouse brain reveals spatiotemporal molecular markers. Sci Rep. 2025 Apr 10;15(1):12299

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    09/08/2026
    MGI 6.24
    The Jackson Laboratory