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Epop Gene Detail
Summary
  • Symbol
    Epop
  • Name
    elongin BC and polycomb repressive complex 2 associated protein
  • Synonyms
    E13, E130012A19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143991
    NCBI Gene: 103551
  • Alliance
    genome feature page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:97518215-97520528 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 61.03 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    120 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2143991
 protein coding gene Chr11:97518213-97520542 (-)
129S1/SvImJ ENSMUSG00200048322
 protein coding gene Chr11:94765153-94767466 (-)
A/J ENSMUSG00195047214
 protein coding gene Chr11:94488849-94491165 (-)
AKR/J ENSMUSG00220050806
 protein coding gene Chr11:94747994-94750310 (-)
BALB/cJ ENSMUSG00180051977
 protein coding gene Chr11:94753515-94755831 (-)
C3H/HeJ ENSMUSG00175038489
 protein coding gene Chr11:94745204-94747517 (-)
C57BL/6NJ ENSMUSG00215053356
 protein coding gene Chr11:94336054-94338367 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017058
 protein coding gene Chr11:93404679-93406992 (-)
CAST/EiJ ENSTCUG00005049096
 protein coding gene Chr11:94199455-94201768 (-)
CBA/J ENSMUSG00210052778
 protein coding gene Chr11:94450918-94453234 (-)
DBA/2J ENSMUSG00185042869
 protein coding gene Chr11:94795109-94797422 (-)
FVB/NJ ENSMUSG00205046208
 protein coding gene Chr11:94655787-94658103 (-)
JF1/MsJ ENSUMUG00000040525
 protein coding gene Chr11:95100913-95103226 (-)
LP/J ENSMUSG00230050011
 protein coding gene Chr11:95848079-95850392 (-)
NOD/ShiLtJ ENSMUSG00190030097
 protein coding gene Chr11:94838124-94840440 (-)
NZO/HlLtJ ENSMUSG00225052051
 protein coding gene Chr11:97902189-97904505 (-)
PWK/PhJ ENSLUMG00010044912
 protein coding gene Chr11:94650873-94653186 (-)
SPRET/EiJ ENSMSPG00010048898
 protein coding gene Chr11:95145145-95147457 (-)
WSB/EiJ ENSIUOG00005047222
 protein coding gene Chr11:94594322-94596635 (-)



Homology
more
  • Human Ortholog
    EPOP, elongin BC and polycomb repressive complex 2 associated protein
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EPOP, elongin BC and polycomb repressive complex 2 associated protein
  • Synonyms
    C17orf96, PRR28
  • Links
    NCBI Gene ID: 100170841
    UniProt: A6NHQ4

  • Chr Location
    17q12; chr17:38671703-38674957 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    652
  • Tissues
    28
  • cDNA Data
    25
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000043439 Ensembl Gene Model | MGI Sequence Detail 2314 C57BL/6J ±  kb
transcript ENSMUST00000052281 Ensembl | MGI Sequence Detail 2314 Not Applicable  
polypeptide ENSMUSP00000051211 Ensembl | MGI Sequence Detail 369 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000059700 elongin BC and Polycomb repressive complex 2-associated protein
    (term hierarchy)
  • InterPro Domains
    IPR027971 Elongin BC and Polycomb repressive complex 2-associated protein EPOP-like
    IPR052119 Elongin BC-PRC2 Interaction & Viral Restriction
  • GlyGen
    Q7TNS8 1 site
Molecular
Reagents
less
  • All nucleic 29
    Genomic 2
    cDNA 26
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2144145, MGI:2144555
References
more
  • Summaries
    All 48
    Developmental Gene Expression 5
    Gene Ontology 7
    Phenotypes 13
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:371338 Mocavini I, et al., The PRC2-associated factor EPOP is required for Hox gene regulation during axial development in mice. Dev Biol. 2025 Aug 18;527:250-259
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory