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Mgat4b Gene Detail
Summary
  • Symbol
    Mgat4b
  • Name
    mannoside acetylglucosaminyltransferase 4, isoenzyme B
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143974
    NCBI Gene: 103534
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:50116162-50125930 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 30.37 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    254 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2143974
 protein coding gene Chr11:50101717-50125930 (+)
129S1/SvImJ ENSMUSG00200040001
 protein coding gene Chr11:47080144-47104366 (+)
A/J ENSMUSG00195035820
 protein coding gene Chr11:47030957-47055181 (+)
AKR/J ENSMUSG00220036793
 protein coding gene Chr11:47221099-47245691 (+)
BALB/cJ ENSMUSG00180035676
 protein coding gene Chr11:47092455-47116679 (+)
C3H/HeJ ENSMUSG00175034821
 protein coding gene Chr11:47062571-47086796 (+)
C57BL/6NJ ENSMUSG00215029527
 protein coding gene Chr11:46989407-47013623 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016285
 protein coding gene Chr11:45102602-45127573 (+)
CAST/EiJ ENSTCUG00005039180
 protein coding gene Chr11:46617761-46642034 (+)
CBA/J ENSMUSG00210029471
 protein coding gene Chr11:46918532-46942752 (+)
DBA/2J ENSMUSG00185026229
 protein coding gene Chr11:47172723-47196943 (+)
FVB/NJ ENSMUSG00205023328
 protein coding gene Chr11:46960333-46984556 (+)
JF1/MsJ ENSUMUG00000037897
 protein coding gene Chr11:47435370-47459665 (+)
LP/J ENSMUSG00230032711
 protein coding gene Chr11:48311876-48336093 (+)
NOD/ShiLtJ ENSMUSG00190035146
 protein coding gene Chr11:47177144-47201364 (+)
NZO/HlLtJ ENSMUSG00225035745
 protein coding gene Chr11:50299544-50324140 (+)
PWK/PhJ ENSLUMG00010027945
 protein coding gene Chr11:46954678-46978934 (+)
SPRET/EiJ ENSMSPG00010019447
 protein coding gene Chr11:47605306-47629336 (+)
WSB/EiJ ENSIUOG00005037831
 protein coding gene Chr11:46979599-47003795 (+)



Homology
more
  • Human Ortholog
    MGAT4B, alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MGAT4B, alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
  • Synonyms
    GNT-IV, GNT-IVB
  • Links
    NCBI Gene ID: 11282
    UniProt: Q9UQ53

  • Chr Location
    5q35.3; chr5:179797597-179806979 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a floxed targeted allele are viable and do not display any gross physical or behavioral abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    729
  • Tissues
    102
  • cDNA Data
    71
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 103534 NCBI Gene Model | MGI Sequence Detail 9769 C57BL/6J ±  kb
    transcript NM_145926 RefSeq | MGI Sequence Detail 2429 C57BL/6  
    polypeptide Q812F8 UniProt | EBI | MGI Sequence Detail 548 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 71
      cDNA 71

      Microarray probesets 2
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 3
      Gene Ontology 10
      Phenotypes 8
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory