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Mrpl33 Gene Detail
Summary
  • Symbol
    Mrpl33
  • Name
    mitochondrial ribosomal protein L33
  • Synonyms
    0610009M10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137225
    NCBI Gene: 66845
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:31771295-31779988 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 17.27 cM, cytoband B1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    313 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2137225
 protein coding gene Chr5:31754279-31821728 (+)
129S1/SvImJ ENSMUSG00200012430
 protein coding gene Chr5:27221521-27289521 (+)
A/J ENSMUSG00195047851
 protein coding gene Chr5:26701440-26769255 (+)
AKR/J ENSMUSG00220007626
 protein coding gene Chr5:26716775-26784799 (+)
BALB/cJ ENSMUSG00180036031
 protein coding gene Chr5:26505990-26573800 (+)
C3H/HeJ ENSMUSG00175039754
 protein coding gene Chr5:28480278-28553492 (+)
C57BL/6NJ ENSMUSG00215028189
 protein coding gene Chr5:27217151-27284911 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027098
 protein coding gene Chr5:26279424-26353155 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210040666
 protein coding gene Chr5:27453441-27521242 (+)
DBA/2J ENSMUSG00185032347
 protein coding gene Chr5:29308358-29376120 (+)
FVB/NJ ENSMUSG00205024731
 protein coding gene Chr5:26204937-26272756 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230040944
 protein coding gene Chr5:33925333-33993335 (+)
NOD/ShiLtJ ENSMUSG00190013474
 protein coding gene Chr5:26472038-26539892 (+)
NZO/HlLtJ ENSMUSG00225019304
 protein coding gene Chr5:39133100-39200859 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    MRPL33, mitochondrial ribosomal protein L33
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPL33, mitochondrial ribosomal protein L33
  • Synonyms
    bL33m, C2orf1, L33mt, MRP-L33, RPL33L
  • Links
    NCBI Gene ID: 9553
    UniProt: O75394

  • Chr Location
    2p23.2; chr2:27771717-27988087 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    28 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    2
  • Radiation induced
    2
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    5 involving Mrpl33
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    115 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    623
  • Tissues
    21
  • cDNA Data
    12
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66845 NCBI Gene Model | MGI Sequence Detail 8694 C57BL/6J ±  kb
transcript NM_025796 RefSeq | MGI Sequence Detail 484 C57BL/6  
polypeptide Q9CQP0 UniProt | EBI | MGI Sequence Detail 65 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 13
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1914095
References
more
  • Summaries
    All 60
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 10
    Phenotypes 28
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory