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Ap3m1 Gene Detail
Summary
  • Symbol
    Ap3m1
  • Name
    adaptor-related protein complex 3, mu 1 subunit
  • Synonyms
    1200013D09Rik, C78982
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929212
    NCBI Gene: 55946
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:21083810-21102603 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 11.58 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    479 from dbSNP Build 142
  • Strain Annotations
    26
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929212
 protein coding gene Chr14:21081510-21102603 (-)
129S1/SvImJ ENSMUSGG00200054891
 protein coding gene Chr14:12873032-12876600 (-)
129S1/SvImJ ENSMUSG00200014506
 protein coding gene Chr14:12877479-12882220 (-)
A/J ENSMUSGG00195055408
 protein coding gene Chr14:13959291-13962859 (-)
A/J ENSMUSG00195019308
 protein coding gene Chr14:13963736-13968485 (-)
AKR/J ENSMUSG00220024166
 protein coding gene Chr14:13094212-13099022 (-)
AKR/J ENSMUSGG00220054607
 protein coding gene Chr14:13089827-13093396 (-)
BALB/cJ ENSMUSG00180036318
 protein coding gene Chr14:13058979-13063720 (-)
BALB/cJ ENSMUSGG00180055291
 protein coding gene Chr14:13054532-13058100 (-)
C3H/HeJ ENSMUSGG00175054824
 protein coding gene Chr14:13115145-13118713 (-)
C3H/HeJ ENSMUSG00175021196
 protein coding gene Chr14:13119529-13124339 (-)
C57BL/6NJ ENSMUSG00215020758
 protein coding gene Chr14:13309183-13313993 (-)
C57BL/6NJ ENSMUSGG00215055489
 protein coding gene Chr14:13304799-13308367 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019003
 protein coding gene Chr14:13796778-13818240 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210025238
 protein coding gene Chr14:13350518-13355320 (-)
CBA/J ENSMUSGG00210054683
 protein coding gene Chr14:13346132-13349700 (-)
DBA/2J ENSMUSG00185033560
 protein coding gene Chr14:17635641-17640382 (-)
DBA/2J ENSMUSGG00185057399
 protein coding gene Chr14:17631194-17634762 (-)
FVB/NJ ENSMUSG00205033335
 protein coding gene Chr14:13192552-13197354 (-)
FVB/NJ ENSMUSGG00205054553
 protein coding gene Chr14:13188166-13191734 (-)
JF1/MsJ no annotation
LP/J ENSMUSGG00230055489
 protein coding gene Chr14:24912963-24916531 (-)
LP/J ENSMUSG00230038191
 protein coding gene Chr14:24917349-24922151 (-)
NOD/ShiLtJ ENSMUSGG00190055010
 protein coding gene Chr14:13345031-13348599 (-)
NOD/ShiLtJ ENSMUSG00190028492
 protein coding gene Chr14:13349478-13354219 (-)
NZO/HlLtJ ENSMUSG00225036180
 protein coding gene Chr14:19153000-19157741 (-)
NZO/HlLtJ ENSMUSGG00225055404
 protein coding gene Chr14:19148553-19152121 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    AP3M1, adaptor related protein complex 3 subunit mu 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AP3M1, adaptor related protein complex 3 subunit mu 1
  • Links
    NCBI Gene ID: 26985
    UniProt: Q9Y2T2

  • Chr Location
    10q22.2; chr10:74120255-74151055 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    136
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 55946 NCBI Gene Model | MGI Sequence Detail 18794 C57BL/6J ±  kb
transcript NM_018829 RefSeq | MGI Sequence Detail 4424 ZRU/MplStud  
polypeptide Q9JKC8 UniProt | EBI | MGI Sequence Detail 418 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 136
    cDNA 136

    Microarray probesets 7
Other
Accession IDs
less
MGI:1353590, MGI:1918977, MGI:2145884
References
more
  • Summaries
    All 42
    Gene Ontology 13
    Phenotypes 6
  • Earliest
    J:20036 Simpson F, et al., Characterization of the adaptor-related protein complex, AP-3. J Cell Biol. 1997 May 19;137(4):835-45
  • Latest
    J:239017 Steinmetz CC, et al., Upregulation of mu3A Drives Homeostatic Plasticity by Rerouting AMPAR into the Recycling Endosomal Pathway. Cell Rep. 2016 Sep 06;16(10):2711-22
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory