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Stam2 Gene Detail
Summary
  • Symbol
    Stam2
  • Name
    signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
  • Synonyms
    1200004O12Rik, 5730456G07Rik, Hbp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929100
    NCBI Gene: 56324
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:52582213-52632212 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 30.41 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1376 from dbSNP Build 142
  • Strain Annotations
    27
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929100
 protein coding gene Chr2:52581676-52632293 (-)
129S1/SvImJ ENSMUSG00200010486
 protein coding gene Chr2:49599475-49600729 (-)
129S1/SvImJ ENSMUSGG00200054903
 protein coding gene Chr2:49615911-49621966 (-)
A/J ENSMUSGG00195054933
 protein coding gene Chr2:49763909-49769968 (-)
A/J ENSMUSG00195010052
 protein coding gene Chr2:49747479-49748733 (-)
AKR/J ENSMUSG00220020451
 protein coding gene Chr2:49879712-49880966 (-)
AKR/J ENSMUSGG00220054729
 protein coding gene Chr2:49896144-49902203 (-)
BALB/cJ ENSMUSGG00180055113
 protein coding gene Chr2:49754994-49761053 (-)
BALB/cJ ENSMUSG00180020119
 protein coding gene Chr2:49738575-49739829 (-)
C3H/HeJ ENSMUSGG00175055029
 protein coding gene Chr2:49788043-49794102 (-)
C3H/HeJ ENSMUSG00175013740
 protein coding gene Chr2:49771614-49772868 (-)
C57BL/6NJ ENSMUSG00215012989
 protein coding gene Chr2:49781186-49782441 (-)
C57BL/6NJ ENSMUSGG00215055589
 protein coding gene Chr2:49797610-49803669 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023559
 protein coding gene Chr2:48005407-48051745 (-)
CAST/EiJ no annotation
CBA/J ENSMUSGG00210054855
 protein coding gene Chr2:49801136-49807195 (-)
CBA/J ENSMUSG00210000678
 protein coding gene Chr2:49784706-49785960 (-)
DBA/2J ENSMUSGG00185057479
 protein coding gene Chr2:49668655-49674713 (-)
DBA/2J ENSMUSG00185002448
 protein coding gene Chr2:49652226-49653480 (-)
FVB/NJ ENSMUSGG00205054399
 protein coding gene Chr2:49472237-49478296 (-)
FVB/NJ ENSMUSG00205001492
 protein coding gene Chr2:49455809-49457063 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230000681
 protein coding gene Chr2:51559790-51561044 (-)
LP/J ENSMUSGG00230055674
 protein coding gene Chr2:51576207-51582266 (-)
NOD/ShiLtJ ENSMUSG00190001836
 protein coding gene Chr2:49699733-49700987 (-)
NOD/ShiLtJ ENSMUSGG00190054906
 protein coding gene Chr2:49716164-49722223 (-)
NZO/HlLtJ ENSMUSGG00225055316
 protein coding gene Chr2:59287350-59293409 (-)
NZO/HlLtJ ENSMUSG00225000299
 protein coding gene Chr2:59270933-59272187 (-)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010010629
 protein coding gene Chr2:50598429-50645678 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    STAM2, signal transducing adaptor molecule 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    STAM2, signal transducing adaptor molecule 2
  • Synonyms
    Hbp, STAM2A, STAM2B
  • Links
    NCBI Gene ID: 10254
    UniProt: O75886

  • Chr Location
    2q23.3; chr2:152116801-152175771 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 2 genetic backgrounds
    3 phenotypes from multigenic genotypes
    16 phenotype references
Mice homozygous for a targeted null mutation exhibit no discernable phenotype; mice are viable and fertile with normal lymphocyte responses.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1021
  • Tissues
    229
  • cDNA Data
    78
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56324 NCBI Gene Model | MGI Sequence Detail 50000 C57BL/6J ±  kb
transcript NM_001418464 RefSeq | MGI Sequence Detail 4498 C57BL/6  
polypeptide O88811 UniProt | EBI | MGI Sequence Detail 523 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 82
    cDNA 80
    Primer pair 1
    Other 1
    Antibodies 1

    Microarray probesets 12
Other
Accession IDs
less
MGI:1917833, MGI:1918967, MGI:2139437
References
more
  • Summaries
    All 58
    Developmental Gene Expression 4
    Gene Ontology 8
    Phenotypes 16
  • Earliest
    J:180803 Gajovic S, et al., Genes expressed after retinoic acid-mediated differentiation of embryoid bodies are likely to be expressed during embryo development. Exp Cell Res. 1998 Jul 10;242(1):138-43
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory