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Epm2aip1 Gene Detail
Summary
  • Symbol
    Epm2aip1
  • Name
    EPM2A interacting protein 1
  • Synonyms
    A930003G21Rik, EPM2A (laforin) interacting protein 1, mKIAA0766
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925031
    NCBI Gene: 77781
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:111100997-111108161 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 60.92 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    252 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925031
 protein coding gene Chr9:111100913-111108161 (+)
129S1/SvImJ ENSMUSG00200038676
 protein coding gene Chr9:108189488-108196647 (+)
A/J ENSMUSG00195036145
 protein coding gene Chr9:107487922-107495083 (+)
AKR/J ENSMUSG00220022642
 protein coding gene Chr9:107823337-107830499 (+)
BALB/cJ ENSMUSG00180028303
 protein coding gene Chr9:107942586-107949748 (+)
C3H/HeJ ENSMUSG00175029775
 protein coding gene Chr9:108158383-108165545 (+)
C57BL/6NJ ENSMUSG00215035923
 protein coding gene Chr9:108038779-108045942 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032756
 protein coding gene Chr9:106550670-106557866 (+)
CAST/EiJ ENSTCUG00005023164
 protein coding gene Chr9:107844890-107852060 (+)
CBA/J ENSMUSG00210028719
 protein coding gene Chr9:107875975-107883134 (+)
DBA/2J ENSMUSG00185038193
 protein coding gene Chr9:108206278-108213440 (+)
FVB/NJ ENSMUSG00205024835
 protein coding gene Chr9:108154400-108161562 (+)
JF1/MsJ ENSUMUG00000036711
 protein coding gene Chr9:107976961-107984120 (+)
LP/J ENSMUSG00230048946
 protein coding gene Chr9:108321572-108328731 (+)
NOD/ShiLtJ ENSMUSG00190044409
 protein coding gene Chr9:107793966-107801128 (+)
NZO/HlLtJ ENSMUSG00225023609
 protein coding gene Chr9:108577244-108584408 (+)
PWK/PhJ ENSLUMG00010027027
 protein coding gene Chr9:107983795-107990954 (+)
SPRET/EiJ ENSMSPG00010045440
 protein coding gene Chr9:109771282-109774085 (+)
WSB/EiJ ENSIUOG00005043939
 protein coding gene Chr9:107247147-107254311 (+)



Homology
more
  • Human Ortholog
    EPM2AIP1, EPM2A interacting protein 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EPM2AIP1, EPM2A interacting protein 1
  • Links
    NCBI Gene ID: 9852
    UniProt: Q7L775

  • Chr Location
    3p22.2; chr3:36985043-36993131 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trapped allele exhibit increased anxiety-related response, decreased liver glycogen storage and synthesis, hepatic steatosis, improved glucose tolerance and decreased hepatic insulin resistance.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    601
  • Tissues
    4
  • cDNA Data
    134
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000046785 Ensembl Gene Model | MGI Sequence Detail 7165 C57BL/6J ±  kb
    transcript ENSMUST00000135807 Ensembl | MGI Sequence Detail 4245 Not Applicable  
    polypeptide ENSMUSP00000120245 Ensembl | MGI Sequence Detail 606 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 134
      cDNA 134

      Microarray probesets 7
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 4
      Gene Ontology 6
      Phenotypes 2
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory