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Mlec Gene Detail
Summary
  • Symbol
    Mlec
  • Name
    malectin
  • Synonyms
    2410014A08Rik, ESTM19, mKIAA0152
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924015
    NCBI Gene: 109154
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:115281040-115296235 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 55.99 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    333 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924015
 protein coding gene Chr5:115281040-115296238 (-)
129S1/SvImJ ENSMUSG00200020560
 protein coding gene Chr5:109023482-109038668 (-)
A/J ENSMUSG00195036634
 protein coding gene Chr5:108535731-108550933 (-)
AKR/J ENSMUSG00220044082
 protein coding gene Chr5:108052856-108068043 (-)
BALB/cJ ENSMUSG00180045098
 protein coding gene Chr5:108674174-108689362 (-)
C3H/HeJ ENSMUSG00175043752
 protein coding gene Chr5:110662006-110677206 (-)
C57BL/6NJ ENSMUSG00215012655
 protein coding gene Chr5:108681936-108697133 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027616
 protein coding gene Chr5:108081030-108096017 (-)
CAST/EiJ ENSTCUG00005020851
 protein coding gene Chr5:107855994-107871029 (-)
CBA/J ENSMUSG00210031428
 protein coding gene Chr5:109413408-109428608 (-)
DBA/2J ENSMUSG00185052360
 protein coding gene Chr5:112472253-112487439 (-)
FVB/NJ ENSMUSG00205029612
 protein coding gene Chr5:108312344-108327546 (-)
JF1/MsJ ENSUMUG00000032423
 protein coding gene Chr5:115289929-115304947 (-)
LP/J ENSMUSG00230045449
 protein coding gene Chr5:116561597-116576782 (-)
NOD/ShiLtJ ENSMUSG00190024982
 protein coding gene Chr5:108350017-108365206 (-)
NZO/HlLtJ ENSMUSG00225015270
 protein coding gene Chr5:124221687-124236872 (-)
PWK/PhJ ENSLUMG00010030450
 protein coding gene Chr5:107194441-107208391 (-)
SPRET/EiJ ENSMSPG00010045786
 protein coding gene Chr5:110479811-110490005 (-)
WSB/EiJ ENSIUOG00005036066
 protein coding gene Chr5:111053882-111069073 (-)



Homology
more
  • Human Ortholog
    MLEC, malectin
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MLEC, malectin
  • Synonyms
    KIAA0152
  • Links
    NCBI Gene ID: 9761
    UniProt: Q14165

  • Chr Location
    12q24.31; chr12:120687125-120704282 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    661
  • Tissues
    9
  • cDNA Data
    15
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 109154 NCBI Gene Model | MGI Sequence Detail 15196 C57BL/6J ±  kb
    transcript NM_175403 RefSeq | MGI Sequence Detail 5970 ZRU/MplStud  
    polypeptide Q6ZQI3 UniProt | EBI | MGI Sequence Detail 291 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 15
      Primer pair 1

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGD-MRK-28124, MGI:104830, MGI:2140989
    References
    more
    • Summaries
      All 51
      Developmental Gene Expression 2
      Gene Ontology 6
      Phenotypes 19
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory