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Ppp4r4 Gene Detail
Summary
  • Symbol
    Ppp4r4
  • Name
    protein phosphatase 4, regulatory subunit 4
  • Synonyms
    8430415E04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921771
    NCBI Gene: 74521
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:103498542-103580090 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 52.95 cM, cytoband F1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2351 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921771
 protein coding gene Chr12:103498509-103580098 (+)
129S1/SvImJ ENSMUSG00200025101
 protein coding gene Chr12:95298578-95380127 (+)
A/J ENSMUSG00195019331
 protein coding gene Chr12:97825377-97906927 (+)
AKR/J ENSMUSG00220035636
 protein coding gene Chr12:95779283-95860828 (+)
BALB/cJ ENSMUSG00180030541
 protein coding gene Chr12:97025291-97106839 (+)
C3H/HeJ ENSMUSG00175029372
 protein coding gene Chr12:99638116-99719664 (+)
C57BL/6NJ ENSMUSG00215038188
 protein coding gene Chr12:96300045-96381596 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018056
 protein coding gene Chr12:98186616-98267055 (+)
CAST/EiJ ENSTCUG00005019070
 protein coding gene Chr12:95670703-95751870 (+)
CBA/J ENSMUSG00210013939
 protein coding gene Chr12:96678634-96760179 (+)
DBA/2J ENSMUSG00185045971
 protein coding gene Chr12:98483306-98564850 (+)
FVB/NJ ENSMUSG00205011323
 protein coding gene Chr12:95690322-95771868 (+)
JF1/MsJ ENSUMUG00000016267
 protein coding gene Chr12:103189637-103274259 (+)
LP/J ENSMUSG00230025099
 protein coding gene Chr12:105563569-105645120 (+)
NOD/ShiLtJ ENSMUSG00190023468
 protein coding gene Chr12:89371276-89452809 (-)
NZO/HlLtJ ENSMUSG00225038022
 protein coding gene Chr12:107264128-107346185 (+)
PWK/PhJ ENSLUMG00010012722
 protein coding gene Chr12:96626820-96708120 (+)
SPRET/EiJ ENSMSPG00010018498
 protein coding gene Chr12:99167262-99251400 (+)
WSB/EiJ ENSIUOG00005008171
 protein coding gene Chr12:95703715-95785302 (+)



Homology
more
  • Human Ortholog
    PPP4R4, protein phosphatase 4 regulatory subunit 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPP4R4, protein phosphatase 4 regulatory subunit 4
  • Synonyms
    CFAP14, KIAA1622, PP4R4
  • Links
    NCBI Gene ID: 57718
    UniProt: Q6NUP7

  • Chr Location
    14q32.12-q32.13; chr14:94146128-94279734 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    607
  • Tissues
    7
  • cDNA Data
    10
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021209 Ensembl Gene Model | MGI Sequence Detail 81549 C57BL/6J ±  kb
transcript ENSMUST00000021631 Ensembl | MGI Sequence Detail 3964 Not Applicable  
polypeptide ENSMUSP00000021631 Ensembl | MGI Sequence Detail 875 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 31
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:244597 Cui W, et al., Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos. Sci Rep. 2016 Nov 21;6:37396
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory