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Osbpl10 Gene Detail
Summary
  • Symbol
    Osbpl10
  • Name
    oxysterol binding protein-like 10
  • Synonyms
    4933433D06Rik, C820004B04Rik, OPR-10
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921736
    NCBI Gene: 74486
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:114807637-115061293 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 66.84 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    9299 from dbSNP Build 142
  • Strain Annotations
    25
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921736
 protein coding gene Chr9:114807531-115062341 (+)
129S1/SvImJ ENSMUSG00200025859
 protein coding gene Chr9:111996169-112001650 (+)
129S1/SvImJ ENSMUSGG00200054584
 protein coding gene Chr9:112016156-112145598 (+)
A/J ENSMUSGG00195055470
 protein coding gene Chr9:111200352-111329464 (+)
A/J ENSMUSG00195032552
 protein coding gene Chr9:111180463-111185947 (+)
AKR/J ENSMUSGG00220054520
 protein coding gene Chr9:111663340-111792923 (+)
AKR/J ENSMUSG00220017868
 protein coding gene Chr9:111643528-111648949 (+)
BALB/cJ ENSMUSG00180027800
 protein coding gene Chr9:111718163-111723645 (+)
BALB/cJ ENSMUSGG00180055509
 protein coding gene Chr9:111738044-111867134 (+)
C3H/HeJ ENSMUSG00175016995
 protein coding gene Chr9:111940131-111945611 (+)
C3H/HeJ ENSMUSGG00175054683
 protein coding gene Chr9:111960002-112089082 (+)
C57BL/6NJ ENSMUSG00215021287
 protein coding gene Chr9:111836062-111841543 (+)
C57BL/6NJ ENSMUSGG00215055322
 protein coding gene Chr9:111863135-111993019 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032779
 protein coding gene Chr9:110434951-110679267 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210032971
 protein coding gene Chr9:111678445-111683924 (+)
CBA/J ENSMUSGG00210054615
 protein coding gene Chr9:111705514-111835388 (+)
DBA/2J ENSMUSGG00185057483
 protein coding gene Chr9:112042243-112172117 (+)
DBA/2J ENSMUSG00185015542
 protein coding gene Chr9:112015171-112020652 (+)
FVB/NJ ENSMUSG00205020023
 protein coding gene Chr9:111840797-111846281 (+)
FVB/NJ ENSMUSGG00205054137
 protein coding gene Chr9:111860957-111989974 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230049651
 protein coding gene Chr9:112043722-112288671 (+)
NOD/ShiLtJ ENSMUSG00190048608
 protein coding gene Chr9:111600098-111605595 (+)
NOD/ShiLtJ ENSMUSGG00190054591
 protein coding gene Chr9:111620116-111750175 (+)
NZO/HlLtJ ENSMUSG00225022903
 protein coding gene Chr9:112315208-112560779 (+)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010020857
 protein coding gene Chr9:113360916-113608942 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    OSBPL10, oxysterol binding protein like 10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OSBPL10, oxysterol binding protein like 10
  • Synonyms
    ORP10, OSBP9
  • Links
    NCBI Gene ID: 114884
    UniProt: Q9BXB5

  • Chr Location
    3p23-p22.3; chr3:31657888-32077692 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    41
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    666
  • Tissues
    19
  • cDNA Data
    16
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000040875 Ensembl Gene Model | MGI Sequence Detail 253657 C57BL/6J ±  kb
    transcript ENSMUST00000183104 Ensembl | MGI Sequence Detail 2477 Not Applicable  
    polypeptide ENSMUSP00000138287 Ensembl | MGI Sequence Detail 766 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      7 Sequences
    • Protein Ontology
      PR:000012045 oxysterol-binding protein-related protein 10
      (term hierarchy)
    • InterPro Domains
      IPR000648 Oxysterol-binding protein
      IPR018494 Oxysterol-binding protein, conserved site
      IPR037239 Oxysterol-binding protein superfamily
      IPR011993 PH-like domain superfamily
      IPR001849 Pleckstrin homology domain
      IPR041680 Pleckstrin homology domain 8
    • GlyGen
      S4R1M9 3 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (2 sites)
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 16
      Primer pair 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2441922
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 2
      Gene Ontology 8
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory