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Rwdd3 Gene Detail
Summary
  • Symbol
    Rwdd3
  • Name
    RWD domain containing 3
  • Synonyms
    2510027J23Rik, 3110037C01Rik, RSUME
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920420
    NCBI Gene: 66568
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:120949047-120965344 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 52.94 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    626 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920420
 protein coding gene Chr3:120949046-120965427 (-)
129S1/SvImJ ENSMUSG00200024536
 protein coding gene Chr3:117631416-117647025 (-)
A/J ENSMUSG00195014331
 protein coding gene Chr3:117851061-117866693 (-)
AKR/J ENSMUSG00220025138
 protein coding gene Chr3:116243020-116258648 (-)
BALB/cJ ENSMUSG00180029322
 protein coding gene Chr3:117787316-117802940 (-)
C3H/HeJ ENSMUSG00175025207
 protein coding gene Chr3:117334454-117350084 (-)
C57BL/6NJ ENSMUSG00215005733
 protein coding gene Chr3:118082645-118098479 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025582
 protein coding gene Chr3:114662922-114680016 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210002868
 protein coding gene Chr3:117965438-117981062 (-)
DBA/2J ENSMUSG00185007183
 protein coding gene Chr3:118537331-118553711 (-)
FVB/NJ ENSMUSG00205007452
 protein coding gene Chr3:116906962-116922583 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230009418
 protein coding gene Chr3:120482114-120497723 (-)
NOD/ShiLtJ ENSMUSG00190025695
 protein coding gene Chr3:118918225-118933847 (-)
NZO/HlLtJ ENSMUSG00225001800
 protein coding gene Chr3:122977101-122992724 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    RWDD3, RWD domain containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RWDD3, RWD domain containing 3
  • Synonyms
    RSUME
  • Links
    NCBI Gene ID: 25950
    UniProt: Q9Y3V2

  • Chr Location
    1p21.3; chr1:95234155-95247685 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    7
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    599
  • Tissues
    1
  • cDNA Data
    17
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028133 Ensembl Gene Model | MGI Sequence Detail 16298 C57BL/6J ±  kb
transcript ENSMUST00000106467 Ensembl | MGI Sequence Detail 1158 Not Applicable  
polypeptide ENSMUSP00000102075 Ensembl | MGI Sequence Detail 339 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    Genomic 2
    cDNA 18

    Microarray probesets 5
Other
Accession IDs
less
MGI:1913818, MGI:2139616, MGI:2139778
References
more
  • Summaries
    All 45
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 7
    Phenotypes 14
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory