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Serp2 Gene Detail
Summary
  • Symbol
    Serp2
  • Name
    stress-associated endoplasmic reticulum protein family member 2
  • Synonyms
    2810032E02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919911
    NCBI Gene: 72661
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:76770254-76794329 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 40.44 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    617 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919911
 protein coding gene Chr14:76770252-76794518 (-)
129S1/SvImJ ENSMUSG00200010265
 protein coding gene Chr14:65196355-65220451 (-)
A/J ENSMUSG00195003998
 protein coding gene Chr14:65347658-65371783 (-)
AKR/J ENSMUSG00220007224
 protein coding gene Chr14:64735319-64759393 (-)
BALB/cJ ENSMUSG00180020311
 protein coding gene Chr14:64939582-64963710 (-)
C3H/HeJ ENSMUSG00175027228
 protein coding gene Chr14:66756407-66780478 (-)
C57BL/6NJ ENSMUSG00215014101
 protein coding gene Chr14:64935119-64959197 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019524
 protein coding gene Chr14:67405090-67428997 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210010104
 protein coding gene Chr14:65371028-65395101 (-)
DBA/2J ENSMUSG00185021731
 protein coding gene Chr14:70515688-70539760 (-)
FVB/NJ ENSMUSG00205019889
 protein coding gene Chr14:64766890-64790962 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230015245
 protein coding gene Chr14:82546302-82570394 (-)
NOD/ShiLtJ ENSMUSG00190010155
 protein coding gene Chr14:65181581-65205653 (-)
NZO/HlLtJ ENSMUSG00225024949
 protein coding gene Chr14:72850699-72874822 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    SERP2, stress associated endoplasmic reticulum protein family member 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SERP2, stress associated endoplasmic reticulum protein family member 2
  • Synonyms
    bA269C23.1, C13orf21
  • Links
    NCBI Gene ID: 387923
    UniProt: Q8N6R1

  • Chr Location
    13q14.11; chr13:44373476-44397714 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    7
  • Targeted
    3
  • Genomic Mutations
    1 involving Serp2
  • Find Mice (IMSR)
    6 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    19
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000052584 Ensembl Gene Model | MGI Sequence Detail 24076 C57BL/6J ±  kb
transcript ENSMUST00000064517 Ensembl | MGI Sequence Detail 748 Not Applicable  
polypeptide ENSMUSP00000068508 Ensembl | MGI Sequence Detail 65 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000014677 stress-associated endoplasmic reticulum protein 2
    (term hierarchy)
  • InterPro Domains
    IPR010580 Stress-associated endoplasmic reticulum protein
Molecular
Reagents
less
  • All nucleic 19
    cDNA 19

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory