About   Help   FAQ
Cyb5rl Gene Detail
Summary
  • Symbol
    Cyb5rl
  • Name
    cytochrome b5 reductase-like
  • Synonyms
    2810410C14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919657
    NCBI Gene: 230582
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:106924035-106945204 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 49.99 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    564 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919657
 protein coding gene Chr4:106924035-106945465 (+)
129S1/SvImJ ENSMUSG00200047365
 protein coding gene Chr4:101978103-102004909 (+)
A/J ENSMUSG00195041766
 protein coding gene Chr4:102520951-102545752 (+)
AKR/J ENSMUSG00220011058
 protein coding gene Chr4:101933505-101954386 (+)
BALB/cJ ENSMUSG00180039123
 protein coding gene Chr4:101368404-101391018 (+)
C3H/HeJ ENSMUSG00175037807
 protein coding gene Chr4:102372911-102393523 (+)
C57BL/6NJ ENSMUSG00215025144
 protein coding gene Chr4:102255225-102276108 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026243
 protein coding gene Chr4:99154276-99176030 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210053149
 protein coding gene Chr4:102005926-102028546 (+)
DBA/2J ENSMUSG00185044499
 protein coding gene Chr4:102697665-102724501 (+)
FVB/NJ ENSMUSG00205015227
 protein coding gene Chr4:100936833-100959432 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230009278
 protein coding gene Chr4:106018768-106039359 (+)
NOD/ShiLtJ ENSMUSG00190043290
 protein coding gene Chr4:101376670-101398344 (+)
NZO/HlLtJ ENSMUSG00225032654
 protein coding gene Chr4:111116261-111143096 (+)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010026505
 protein coding gene Chr4:102688804-102707659 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CYB5RL, cytochrome b5 reductase like
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYB5RL, cytochrome b5 reductase like
  • Links
    NCBI Gene ID: 606495
    UniProt: Q6IPT4

  • Chr Location
    1p32.3; chr1:54169651-54200073 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    2
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    5
  • Genomic Mutations
    4 involving Cyb5rl
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    28 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    627
  • Tissues
    6
  • cDNA Data
    23
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 230582 NCBI Gene Model | MGI Sequence Detail 21170 C57BL/6J ±  kb
transcript NM_175471 RefSeq | MGI Sequence Detail 5235 C57BL/6  
polypeptide B1AS42 UniProt | EBI | MGI Sequence Detail 316 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    9 Sequences
  • Protein Ontology
    PR:000006084 NADH-cytochrome b5 reductase-like
    (term hierarchy)
  • EC
    1.6.2.2
  • InterPro Domains
    IPR017927 FAD-binding domain, ferredoxin reductase-type
    IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain
    IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase
    IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain
    IPR001834 NADH:cytochrome b5 reductase-like
    IPR001433 Oxidoreductase FAD/NAD(P)-binding
    IPR039251 Oxidoreductase-like domain-containing protein 1
    IPR019180 Oxidoreductase-like, N-terminal
    IPR017938 Riboflavin synthase-like beta-barrel
Molecular
Reagents
less
  • All nucleic 23
    cDNA 23

    Microarray probesets 4
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory