About   Help   FAQ
Sft2d1 Gene Detail
Summary
  • Symbol
    Sft2d1
  • Name
    SFT2 domain containing 1
  • Synonyms
    5630401J11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918689
    NCBI Gene: 106489
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:8529934-8546274 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 4.92 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    539 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918689
 protein coding gene Chr17:8529920-8546274 (+)
129S1/SvImJ ENSMUSG00200032926
 protein coding gene Chr17:4771491-4787838 (+)
A/J ENSMUSG00195022956
 protein coding gene Chr17:4979996-4996316 (+)
AKR/J ENSMUSG00220025455
 protein coding gene Chr17:5038560-5054918 (+)
BALB/cJ ENSMUSG00180021491
 protein coding gene Chr17:4626220-4642541 (+)
C3H/HeJ ENSMUSG00175031049
 protein coding gene Chr17:4770514-4786835 (+)
C57BL/6NJ ENSMUSG00215025230
 protein coding gene Chr17:4772225-4788565 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021062
 protein coding gene Chr17:8473599-8551707 (-)
CAST/EiJ ENSTCUG00005021819
 protein coding gene Chr17:5015764-5032134 (+)
CBA/J ENSMUSG00210034750
 protein coding gene Chr17:4437325-4453646 (+)
DBA/2J ENSMUSG00185022105
 protein coding gene Chr17:5529970-5546291 (+)
FVB/NJ ENSMUSG00205008339
 protein coding gene Chr17:4843118-4859439 (+)
JF1/MsJ ENSUMUG00000016648
 protein coding gene Chr17:5131288-5147633 (+)
LP/J ENSMUSG00230031995
 protein coding gene Chr17:6958896-6975250 (+)
NOD/ShiLtJ ENSMUSG00190031407
 protein coding gene Chr17:4975730-4992051 (+)
NZO/HlLtJ ENSMUSG00225028990
 protein coding gene Chr17:8879186-8895540 (+)
PWK/PhJ ENSLUMG00010018420
 protein coding gene Chr17:4944672-4960972 (+)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005013546
 protein coding gene Chr17:4828662-4844991 (+)



Homology
more
  • Human Ortholog
    SFT2D1, SFT2 domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SFT2D1, SFT2 domain containing 1
  • Synonyms
    C6orf83, pRGR1
  • Links
    NCBI Gene ID: 113402
    UniProt: Q8WV19

  • Chr Location
    6q27; chr6:166319724-166342590 (-)  GRCh38
Human Diseases
less
  • References
    6 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    372 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    68
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000073468 Ensembl Gene Model | MGI Sequence Detail 16341 C57BL/6J ±  kb
transcript ENSMUST00000154553 Ensembl | MGI Sequence Detail 1049 Not Applicable  
polypeptide ENSMUSP00000117294 Ensembl | MGI Sequence Detail 159 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 68
    cDNA 68

    Microarray probesets 5
Other
Accession IDs
less
MGI:2146762
References
more
  • Summaries
    All 397
    Diseases 6
    Gene Ontology 3
    Phenotypes 372
  • Earliest
    J:30229 Davisson MT, et al., Segmental trisomy as a mouse model for Down syndrome. Prog Clin Biol Res. 1993;384:117-33
  • Latest
    J:391449 Thibodeau J, et al., Loss of cystathionine-beta-synthase contributes to elevated OXPHOS, a vulnerability in Ara-C-resistant Myeloid Leukemia in Down syndrome. Biochem Pharmacol. 2026 Feb 13;247:117815
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory