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Amtn Gene Detail
Summary
  • Symbol
    Amtn
  • Name
    amelotin
  • Synonyms
    5430427O21Rik
Location &
Maps
more
  • Sequence Map
    Chr5:88523967-88533775 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 43.56 cM, cytoband E2
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    364 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918671
 protein coding gene Chr5:88523967-88533775 (+)
129S1/SvImJ ENSMUSG00200009116
 protein coding gene Chr5:84251435-84261293 (+)
A/J ENSMUSG00195025573
 protein coding gene Chr5:83425605-83435415 (+)
AKR/J ENSMUSG00220011400
 protein coding gene Chr5:83566022-83575831 (+)
BALB/cJ ENSMUSG00180022970
 protein coding gene Chr5:83254457-83264315 (+)
C3H/HeJ ENSMUSG00175038062
 protein coding gene Chr5:85340851-85350709 (+)
C57BL/6NJ ENSMUSG00215027686
 protein coding gene Chr5:84118661-84128469 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027371
 protein coding gene Chr5:81672909-81684284 (+)
CAST/EiJ ENSTCUG00005032012
 protein coding gene Chr5:83078948-83088809 (+)
CBA/J ENSMUSG00210005755
 protein coding gene Chr5:84144886-84154743 (+)
DBA/2J ENSMUSG00185038441
 protein coding gene Chr5:86064102-86073960 (+)
FVB/NJ ENSMUSG00205018022
 protein coding gene Chr5:82962885-82972693 (+)
JF1/MsJ ENSUMUG00000000487
 protein coding gene Chr5:90419493-90429330 (+)
LP/J ENSMUSG00230001069
 protein coding gene Chr5:90781412-90791270 (+)
NOD/ShiLtJ ENSMUSG00190026363
 protein coding gene Chr5:83011859-83021717 (+)
NZO/HlLtJ ENSMUSG00225008312
 protein coding gene Chr5:95939429-95949321 (+)
PWK/PhJ ENSLUMG00010028693
 protein coding gene Chr5:83098204-83108027 (+)
SPRET/EiJ ENSMSPG00010029545
 protein coding gene Chr5:85507700-85517743 (+)
WSB/EiJ ENSIUOG00005026726
 protein coding gene Chr5:86049488-86059315 (+)



Homology
more
  • Human Ortholog
    AMTN, amelotin
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AMTN, amelotin
  • Synonyms
    AI3B, UNQ689
  • Links
    NCBI Gene ID: 401138
    UniProt: Q6UX39

  • Chr Location
    4q13.3; chr4:70518569-70532743 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human AMTN associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 2 genetic backgrounds
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit enamel hypomineralization.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    10
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    601
  • Tissues
    1
  • cDNA Data
    4
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 71421 NCBI Gene Model | MGI Sequence Detail 9809 C57BL/6J ±  kb
    transcript NM_027793 RefSeq | MGI Sequence Detail 1022 C57BL/6  
    polypeptide Q9D3J8 UniProt | EBI | MGI Sequence Detail 213 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 4
      cDNA 4
      Antibodies 1

      Microarray probesets 2
    References
    more
    • Summaries
      All 50
      Developmental Gene Expression 5
      Gene Ontology 10
      Phenotypes 18
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory