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Pnrc1 Gene Detail
Summary
  • Symbol
    Pnrc1
  • Name
    proline-rich nuclear receptor coactivator 1
  • Synonyms
    5730463C12Rik, B4-2, Prol2, PRR2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917838
    NCBI Gene: 108767
  • Alliance
    genome feature page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:33245423-33248787 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 14.75 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    129 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917838
 protein coding gene Chr4:33245423-33290163 (-)
129S1/SvImJ ENSMUSG00200012069
 protein coding gene Chr4:29936873-29943344 (-)
A/J ENSMUSG00195002717
 protein coding gene Chr4:30456242-30462723 (-)
AKR/J ENSMUSG00220014277
 protein coding gene Chr4:30248547-30296524 (-)
BALB/cJ ENSMUSG00180000142
 protein coding gene Chr4:29959323-30007297 (-)
C3H/HeJ ENSMUSG00175002272
 protein coding gene Chr4:30431079-30437560 (-)
C57BL/6NJ ENSMUSG00215000783
 protein coding gene Chr4:30043196-30049677 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025874
 protein coding gene Chr4:27823834-27866936 (-)
CAST/EiJ ENSTCUG00005000267
 protein coding gene Chr4:29935754-29942246 (-)
CBA/J ENSMUSG00210004411
 protein coding gene Chr4:30155696-30203686 (-)
DBA/2J ENSMUSG00185000243
 protein coding gene Chr4:30228142-30234623 (-)
FVB/NJ ENSMUSG00205000369
 protein coding gene Chr4:29813312-29861316 (-)
JF1/MsJ ENSUMUG00000001422
 protein coding gene Chr4:30266889-30314488 (-)
LP/J ENSMUSG00230000876
 protein coding gene Chr4:33514815-33562526 (-)
NOD/ShiLtJ ENSMUSG00190000206
 protein coding gene Chr4:30152454-30200457 (-)
NZO/HlLtJ ENSMUSG00225008429
 protein coding gene Chr4:37458164-37464645 (-)
PWK/PhJ ENSLUMG00010007488
 protein coding gene Chr4:29717685-29720767 (-)
SPRET/EiJ ENSMSPG00010020514
 protein coding gene Chr4:30551992-30558167 (-)
WSB/EiJ ENSIUOG00005004730
 protein coding gene Chr4:29960192-29966655 (-)



Homology
more
  • Human Ortholog
    PNRC1, proline rich nuclear receptor coactivator 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PNRC1, proline rich nuclear receptor coactivator 1
  • Synonyms
    B4-2, PNAS-145, PROL2, PRR2
  • Links
    NCBI Gene ID: 10957
    UniProt: Q12796

  • Chr Location
    6q15; chr6:89080751-89085160 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    24
  • Chemically and radiation induced
    1
  • Endonuclease-mediated
    3
  • Gene trapped
    18
  • Targeted
    2
  • Genomic Mutations
    1 involving Pnrc1
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    20 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    692
  • Tissues
    95
  • cDNA Data
    98
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 108767 NCBI Gene Model | MGI Sequence Detail 3365 C57BL/6J ±  kb
transcript NM_001033225 RefSeq | MGI Sequence Detail 1940 C57BL/6  
polypeptide NP_001028397 RefSeq | MGI Sequence Detail 297 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR026780 Proline-rich nuclear receptor coactivator 1/2
    IPR028322 Proline-rich nuclear receptor coactivator-like, proline rich region
Molecular
Reagents
less
  • All nucleic 100
    cDNA 98
    Primer pair 1
    Other 1

    Microarray probesets 7
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:209112 Shimizu H, et al., The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory