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Adamdec1 Gene Detail
Summary
  • Symbol
    Adamdec1
  • Name
    ADAM-like, decysin 1
  • Synonyms
    2210414L24Rik, Dcsn
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917650
    NCBI Gene: 58860
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:68800829-68819535 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 35.69 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    769 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917650
 protein coding gene Chr14:68800829-68819544 (-)
129S1/SvImJ ENSMUSG00200026909
 protein coding gene Chr14:57421263-57439939 (-)
A/J ENSMUSG00195013788
 protein coding gene Chr14:57591021-57609736 (-)
AKR/J ENSMUSG00220026501
 protein coding gene Chr14:56924162-56942875 (-)
BALB/cJ ENSMUSG00180031301
 protein coding gene Chr14:57199680-57218395 (-)
C3H/HeJ ENSMUSG00175033016
 protein coding gene Chr14:58958202-58976880 (-)
C57BL/6NJ ENSMUSG00215013582
 protein coding gene Chr14:57136255-57154965 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019455
 protein coding gene Chr14:59695328-59714134 (-)
CAST/EiJ ENSTCUG00005035183
 protein coding gene Chr14:58837898-58856614 (-)
CBA/J ENSMUSG00210034513
 protein coding gene Chr14:57576115-57594838 (-)
DBA/2J ENSMUSG00185023179
 protein coding gene Chr14:62756078-62774754 (-)
FVB/NJ ENSMUSG00205025719
 protein coding gene Chr14:57085446-57104160 (-)
JF1/MsJ ENSUMUG00000032811
 protein coding gene Chr14:73931692-73950364 (-)
LP/J no annotation
NOD/ShiLtJ ENSMUSG00190034229
 protein coding gene Chr14:57370863-57389586 (-)
NZO/HlLtJ ENSMUSG00225038598
 protein coding gene Chr14:65098142-65116873 (-)
PWK/PhJ ENSLUMG00010030939
 protein coding gene Chr14:56794766-56813399 (-)
SPRET/EiJ ENSMSPG00010028501
 protein coding gene Chr14:60296429-60314402 (-)
WSB/EiJ ENSIUOG00005035097
 protein coding gene Chr14:56823472-56842085 (-)



Homology
more
  • Human Ortholog
    ADAMDEC1, ADAM like decysin 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ADAMDEC1, ADAM like decysin 1
  • Synonyms
    M12.219
  • Links
    NCBI Gene ID: 27299
    UniProt: O15204

  • Chr Location
    8p21.2; chr8:24384285-24406013 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele are more susceptible to the induction of bacterial and chemical induced colitis, showing more weight loss, increased mortality, increased neutrophil infiltration and greater IL-6 and Il-1beta secretion.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    627
  • Tissues
    6
  • cDNA Data
    31
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 58860 NCBI Gene Model | MGI Sequence Detail 18707 C57BL/6J ±  kb
    transcript NM_021475 RefSeq | MGI Sequence Detail 2433 C57BL/6  
    polypeptide Q9R0X2 UniProt | EBI | MGI Sequence Detail 467 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 31
      cDNA 31

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2145672
    References
    more
    • Summaries
      All 49
      Developmental Gene Expression 5
      Gene Ontology 4
      Phenotypes 13
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345835 Qiu C, et al., A single-cell time-lapse of mouse prenatal development from gastrula to birth. Nature. 2024 Feb;626(8001):1084-1093
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory