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Steap1 Gene Detail
Summary
  • Symbol
    Steap1
  • Name
    six transmembrane epithelial antigen of the prostate 1
  • Synonyms
    2410007B19Rik, Prss24
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917608
    NCBI Gene: 70358
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:5786322-5799317 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 3.20 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    570 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917608
 protein coding gene Chr5:5786317-5799326 (-)
129S1/SvImJ ENSMUSG00200002657
 protein coding gene Chr5:2444988-2465168 (-)
A/J ENSMUSG00195007037
 protein coding gene Chr5:2479578-2492580 (-)
AKR/J ENSMUSG00220001807
 protein coding gene Chr5:2383818-2396827 (-)
BALB/cJ ENSMUSG00180015236
 protein coding gene Chr5:2266895-2279904 (-)
C3H/HeJ ENSMUSG00175025748
 protein coding gene Chr5:2416345-2429347 (-)
C57BL/6NJ ENSMUSG00215021011
 protein coding gene Chr5:2698238-2711247 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026950
 protein coding gene Chr5:2605605-2618540 (-)
CAST/EiJ ENSTCUG00005001276
 protein coding gene Chr5:2604445-2622153 (-)
CBA/J ENSMUSG00210002237
 protein coding gene Chr5:2780935-2793939 (-)
DBA/2J ENSMUSG00185027107
 protein coding gene Chr5:2784707-2797709 (-)
FVB/NJ ENSMUSG00205007115
 protein coding gene Chr5:2489824-2509998 (-)
JF1/MsJ ENSUMUG00000003316
 protein coding gene Chr5:2834119-2847260 (-)
LP/J ENSMUSG00230002143
 protein coding gene Chr5:6695484-6715662 (-)
NOD/ShiLtJ ENSMUSG00190012474
 protein coding gene Chr5:2467136-2480275 (-)
NZO/HlLtJ ENSMUSG00225007929
 protein coding gene Chr5:10465035-10478044 (-)
PWK/PhJ ENSLUMG00010019007
 protein coding gene Chr5:2753996-2767074 (-)
SPRET/EiJ ENSMSPG00010004931
 protein coding gene Chr5:2615546-2628244 (-)
WSB/EiJ ENSIUOG00005022658
 protein coding gene Chr5:2485436-2505609 (-)



Homology
more
  • Human Ortholog
    STEAP1, STEAP family member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    STEAP1, STEAP family member 1
  • Synonyms
    PRSS24, STEAP
  • Links
    NCBI Gene ID: 26872
    UniProt: Q9UHE8

  • Chr Location
    7q21.13; chr7:90154436-90164829 (+)  GRCh38
  • Human Ortholog
    STEAP1B, STEAP family member 1B
  • Links
    NCBI Gene ID: 256227
    UniProt: Q6NZ63

  • Chr Location
    7p15.3; chr7:22417857-22727613 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    642
  • Tissues
    30
  • cDNA Data
    8
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 70358 NCBI Gene Model | MGI Sequence Detail 12996 C57BL/6J ±  kb
transcript NM_027399 RefSeq | MGI Sequence Detail 1216 C57BL/6  
polypeptide Q9CWR7 UniProt | EBI | MGI Sequence Detail 339 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 8
    Primer pair 2

    Microarray probesets 4
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:199301 Lavado A, et al., Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug;140(16):3323-34
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory