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Kyat1 Gene Detail
Summary
  • Symbol
    Kyat1
  • Name
    kynurenine aminotransferase 1
  • Synonyms
    2010009K05Rik, Ccbl1, cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase), Kat1, KATI
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917516
    NCBI Gene: 70266
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:30075136-30095859 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 21.31 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    475 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917516
 protein coding gene Chr2:30075136-30096307 (-)
129S1/SvImJ ENSMUSG00200050044
 protein coding gene Chr2:27045625-27066341 (-)
A/J ENSMUSG00195039381
 protein coding gene Chr2:27138988-27159704 (-)
AKR/J ENSMUSG00220049527
 protein coding gene Chr2:27257533-27278253 (-)
BALB/cJ ENSMUSG00180053142
 protein coding gene Chr2:27158514-27179243 (-)
C3H/HeJ ENSMUSG00175052710
 protein coding gene Chr2:27127828-27148556 (-)
C57BL/6NJ ENSMUSG00215041959
 protein coding gene Chr2:27193255-27213985 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023385
 protein coding gene Chr2:26061980-26084397 (-)
CAST/EiJ ENSTCUG00005052603
 protein coding gene Chr2:26867507-26888425 (-)
CBA/J ENSMUSG00210016882
 protein coding gene Chr2:27200760-27221485 (-)
DBA/2J ENSMUSG00185044391
 protein coding gene Chr2:27053047-27073762 (-)
FVB/NJ ENSMUSG00205042550
 protein coding gene Chr2:26905112-26925838 (-)
JF1/MsJ ENSUMUG00000038176
 protein coding gene Chr2:26952184-26972898 (-)
LP/J ENSMUSG00230043598
 protein coding gene Chr2:28981343-29002061 (-)
NOD/ShiLtJ ENSMUSG00190047234
 protein coding gene Chr2:27159787-27180509 (-)
NZO/HlLtJ ENSMUSG00225008330
 protein coding gene Chr2:36730938-36751654 (-)
PWK/PhJ ENSLUMG00010050218
 protein coding gene Chr2:27029491-27050229 (-)
SPRET/EiJ ENSMSPG00010039353
 protein coding gene Chr2:27761200-27784123 (-)
WSB/EiJ ENSIUOG00005048063
 protein coding gene Chr2:27012749-27033256 (-)



Homology
more
  • Human Ortholog
    KYAT1, kynurenine aminotransferase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KYAT1, kynurenine aminotransferase 1
  • Synonyms
    CCBL1, GTK, KAT1, KATI
  • Links
    NCBI Gene ID: 883
    UniProt: Q16773

  • Chr Location
    9q34.11; chr9:128819663-128882556 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    32
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    955
  • Tissues
    139
  • cDNA Data
    53
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000039648 Ensembl Gene Model | MGI Sequence Detail 20724 C57BL/6J ±  kb
    transcript ENSMUST00000044038 Ensembl | MGI Sequence Detail 1876 Not Applicable  
    polypeptide ENSMUSP00000038612 Ensembl | MGI Sequence Detail 424 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 54
      cDNA 54

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2138852
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 4
      Gene Ontology 10
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:390093 Bowman CE, et al., Off-target depletion of plasma tryptophan by allosteric inhibitors of BCKDK. Mol Metab. 2025 Jul;97:102165
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory