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Ints4 Gene Detail
Summary
  • Symbol
    Ints4
  • Name
    integrator complex subunit 4
  • Synonyms
    2610034N24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917164
    NCBI Gene: 101861
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:97130163-97190602 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 53.52 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2086 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917164
 protein coding gene Chr7:97130158-97190605 (+)
129S1/SvImJ ENSMUSG00200047313
 protein coding gene Chr7:83953563-84014600 (+)
A/J ENSMUSG00195037461
 protein coding gene Chr7:88458530-88519566 (+)
AKR/J ENSMUSG00220048900
 protein coding gene Chr7:81875769-81936823 (+)
BALB/cJ ENSMUSG00180034960
 protein coding gene Chr7:85131918-85192952 (+)
C3H/HeJ ENSMUSG00175021893
 protein coding gene Chr7:85780705-85840641 (+)
C57BL/6NJ ENSMUSG00215012424
 protein coding gene Chr7:84971362-85031964 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030004
 protein coding gene Chr7:100143825-100208548 (+)
CAST/EiJ ENSTCUG00005028595
 protein coding gene Chr7:88344118-88411195 (+)
CBA/J ENSMUSG00210025160
 protein coding gene Chr7:85628680-85688613 (+)
DBA/2J ENSMUSG00185030301
 protein coding gene Chr7:89955392-90015326 (+)
FVB/NJ ENSMUSG00205015977
 protein coding gene Chr7:85633146-85694191 (+)
JF1/MsJ ENSUMUG00000048685
 protein coding gene Chr7:94855265-94915173 (+)
LP/J ENSMUSG00230038334
 protein coding gene Chr7:96070637-96131671 (+)
NOD/ShiLtJ ENSMUSG00190020859
 protein coding gene Chr7:85899765-85960796 (+)
NZO/HlLtJ ENSMUSG00225049706
 protein coding gene Chr7:94257053-94318087 (+)
PWK/PhJ ENSLUMG00010045527
 protein coding gene Chr7:84077961-84138039 (+)
SPRET/EiJ ENSMSPG00010012153
 protein coding gene Chr7:85299048-85362555 (+)
WSB/EiJ ENSIUOG00005009205
 protein coding gene Chr7:86241131-86301968 (+)



Homology
more
  • Human Ortholog
    INTS4, integrator complex subunit 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    INTS4, integrator complex subunit 4
  • Synonyms
    INT4, MST093
  • Links
    NCBI Gene ID: 92105
    UniProt: Q96HW7

  • Chr Location
    11q14.1; chr11:77874362-77994850 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    29 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    31
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    642
  • Tissues
    5
  • cDNA Data
    102
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025133 Ensembl Gene Model | MGI Sequence Detail 60440 C57BL/6J ±  kb
transcript ENSMUST00000026126 Ensembl | MGI Sequence Detail 3240 Not Applicable  
polypeptide ENSMUSP00000026126 Ensembl | MGI Sequence Detail 964 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 102
    cDNA 102

    Microarray probesets 3
Other
Accession IDs
less
MGI:2142238, MGI:3034609
References
more
  • Summaries
    All 58
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 29
  • Earliest
    J:141526 Russell LB, et al., Analysis of the albino-locus region of the mouse. III. Time of death of prenatal lethals. Genetics. 1979 May;92(1):205-13
  • Latest
    J:383550 St-Denis N, et al., Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators. Cell Rep. 2016 Nov 22;17(9):2488-2501
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory