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Rhou Gene Detail
Summary
  • Symbol
    Rhou
  • Name
    ras homolog family member U
  • Synonyms
    2310026M05Rik, Arhu, CDC42L1, mG28K, WRCH-1, WRCH1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916831
    NCBI Gene: 69581
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:124380668-124390623 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 72.10 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    243 from dbSNP Build 142
  • Strain Annotations
    30
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916831
 protein coding gene Chr8:124380609-124390623 (+)
129S1/SvImJ ENSMUSG00200042584
 protein coding gene Chr8:118635665-118637190 (+)
129S1/SvImJ ENSMUSG00200042590
 protein coding gene Chr8:118626710-118636020 (+)
A/J ENSMUSG00195025553
 protein coding gene Chr8:118939300-118940829 (+)
A/J ENSMUSG00195025565
 protein coding gene Chr8:118930338-118939653 (+)
AKR/J ENSMUSG00220039908
 protein coding gene Chr8:119117585-119119114 (+)
AKR/J ENSMUSG00220039913
 protein coding gene Chr8:119108624-119117938 (+)
BALB/cJ ENSMUSG00180024576
 protein coding gene Chr8:118975279-118984596 (+)
BALB/cJ ENSMUSG00180024562
 protein coding gene Chr8:118984242-118985771 (+)
C3H/HeJ ENSMUSG00175028682
 protein coding gene Chr8:119037102-119038630 (+)
C3H/HeJ ENSMUSG00175028696
 protein coding gene Chr8:119028139-119037456 (+)
C57BL/6NJ ENSMUSG00215015962
 protein coding gene Chr8:118612192-118621510 (+)
C57BL/6NJ ENSMUSG00215015946
 protein coding gene Chr8:118621157-118622686 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031695
 protein coding gene Chr8:114812171-114822076 (+)
CAST/EiJ ENSTCUG00005033923
 protein coding gene Chr8:118367246-118377682 (+)
CBA/J ENSMUSG00210033385
 protein coding gene Chr8:118947053-118948582 (+)
CBA/J ENSMUSG00210033391
 protein coding gene Chr8:118938093-118947406 (+)
DBA/2J ENSMUSG00185035056
 protein coding gene Chr8:125265950-125267479 (+)
DBA/2J ENSMUSG00185035076
 protein coding gene Chr8:125256990-125266303 (+)
FVB/NJ ENSMUSG00205029721
 protein coding gene Chr8:117929752-117931281 (+)
FVB/NJ ENSMUSG00205029751
 protein coding gene Chr8:117920792-117930105 (+)
JF1/MsJ ENSUMUG00000023329
 protein coding gene Chr8:127479822-127490260 (+)
LP/J ENSMUSG00230027650
 protein coding gene Chr8:128818388-128819860 (+)
LP/J ENSMUSG00230027684
 protein coding gene Chr8:128809433-128818711 (+)
NOD/ShiLtJ ENSMUSG00190018784
 protein coding gene Chr8:119060188-119070804 (+)
NZO/HlLtJ ENSMUSG00225019752
 protein coding gene Chr8:132191981-132201296 (+)
NZO/HlLtJ ENSMUSG00225019746
 protein coding gene Chr8:132200943-132202472 (+)
PWK/PhJ ENSLUMG00010033869
 protein coding gene Chr8:118764979-118774241 (+)
SPRET/EiJ ENSMSPG00010032012
 protein coding gene Chr8:120963951-120974326 (+)
WSB/EiJ ENSIUOG00005028165
 protein coding gene Chr8:119745991-119755304 (+)



Homology
more
  • Human Ortholog
    RHOU, ras homolog family member U
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RHOU, ras homolog family member U
  • Synonyms
    ARHU, CDC42L1, G28K, hG28K, WRCH1
  • Links
    NCBI Gene ID: 58480
    UniProt: Q7L0Q8

  • Chr Location
    1q42.13; chr1:228644647-228746669 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    35
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    646
  • Tissues
    23
  • cDNA Data
    70
  • Literature Summary
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039960 Ensembl Gene Model | MGI Sequence Detail 9956 C57BL/6J ±  kb
transcript ENSMUST00000045487 Ensembl | MGI Sequence Detail 3371 Not Applicable  
polypeptide ENSMUSP00000038915 Ensembl | MGI Sequence Detail 261 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 75
    cDNA 70
    Primer pair 4
    Other 1
    Antibodies 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2142472
References
more
  • Summaries
    All 50
    Developmental Gene Expression 8
    Gene Ontology 8
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:370212 Hu L, et al., Mettl3 Regulates Lens Development by Promoting the Differentiation Processes of Secondary Fiber Cells. Invest Ophthalmol Vis Sci. 2025 Jul 1;66(9):45
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory