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Fmo2 Gene Detail
Summary
  • Symbol
    Fmo2
  • Name
    flavin containing monooxygenase 2
  • Synonyms
    2310008D08Rik, 2310042I22Rik, MGC:28212
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916776
    NCBI Gene: 55990
  • Alliance
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:162701886-162726295 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 70.34 cM, cytoband H1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    786 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916776
protein coding gene Chr1:162701886-162726327 (-)
129S1/SvImJ ENSMUSG00200005171
protein coding gene Chr1:160175034-160199592 (-)
A/J ENSMUSG00195020369
protein coding gene Chr1:159515169-159539731 (-)
AKR/J ENSMUSG00220013623
protein coding gene Chr1:159315146-159339545 (-)
BALB/cJ ENSMUSG00180034051
protein coding gene Chr1:159752834-159777379 (-)
C3H/HeJ ENSMUSG00175035601
protein coding gene Chr1:159841740-159866298 (-)
C57BL/6NJ ENSMUSG00215036003
protein coding gene Chr1:159722267-159746661 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014778
protein coding gene Chr1:153414298-153438414 (-)
CAST/EiJ ENSTCUG00005019205
protein coding gene Chr1:158334210-158358858 (-)
CBA/J ENSMUSG00210020971
protein coding gene Chr1:159720681-159745240 (-)
DBA/2J ENSMUSG00185011333
protein coding gene Chr1:163970394-163994944 (-)
FVB/NJ ENSMUSG00205008060
protein coding gene Chr1:158800276-158824651 (-)
JF1/MsJ ENSUMUG00000011033
protein coding gene Chr1:163119844-163144433 (-)
LP/J ENSMUSG00230020633
protein coding gene Chr1:163585485-163610041 (-)
NOD/ShiLtJ ENSMUSG00190024795
protein coding gene Chr1:159560732-159585109 (-)
NZO/HlLtJ ENSMUSG00225004233
protein coding gene Chr1:167175796-167200356 (-)
PWK/PhJ ENSLUMG00010038906
protein coding gene Chr1:158518367-158542930 (-)
SPRET/EiJ ENSMSPG00010038984
protein coding gene Chr1:161938101-161962829 (-)
WSB/EiJ ENSIUOG00005015486
protein coding gene Chr1:159082546-159104938 (-)



Homology
more
  • Human Ortholog
    FMO2, flavin containing dimethylaniline monoxygenase 2
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FMO2, flavin containing dimethylaniline monoxygenase 2
  • Synonyms
    FMO1B1
  • Links
    NCBI Gene ID: 2327
    UniProt: Q99518

  • Chr Location
    1q24.3; chr1:171185249-171212686 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040170 Ensembl Gene Model | MGI Sequence Detail 24410 C57BL/6J ±  kb
transcript ENSMUST00000111510 Ensembl | MGI Sequence Detail 2260 Not Applicable  
polypeptide ENSMUSP00000107135 Ensembl | MGI Sequence Detail 535 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 52
    cDNA 49
    Primer pair 3

    Microarray probesets 7
Other
Accession IDs
less
MGI:1923713, MGI:2138560
References
more
  • Summaries
    All 49
    Developmental Gene Expression 9
    Gene Ontology 8
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:328119 Yoshida Y, et al., Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism. Sci Rep. 2022 Sep 1;12(1):14883

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory