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Ngdn Gene Detail
Summary
  • Symbol
    Ngdn
  • Name
    neuroguidin, EIF4E binding protein
  • Synonyms
    1500001L15Rik, neuroguidin, Ngd
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916216
    NCBI Gene: 68966
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:55252911-55261594 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 28.03 cM, cytoband C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    334 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916216
 protein coding gene Chr14:55252911-55261595 (+)
129S1/SvImJ ENSMUSG00200039924
 protein coding gene Chr14:43833201-43841803 (+)
A/J ENSMUSG00195027928
 protein coding gene Chr14:44057554-44066156 (+)
AKR/J ENSMUSG00220027399
 protein coding gene Chr14:43385482-43394086 (+)
BALB/cJ ENSMUSG00180049755
 protein coding gene Chr14:43681285-43689887 (+)
C3H/HeJ ENSMUSG00175047479
 protein coding gene Chr14:45363661-45372263 (+)
C57BL/6NJ ENSMUSG00215045925
 protein coding gene Chr14:43576036-43584719 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019285
 protein coding gene Chr14:46445064-46453877 (+)
CAST/EiJ ENSTCUG00005048097
 protein coding gene Chr14:45360748-45369452 (+)
CBA/J ENSMUSG00210036737
 protein coding gene Chr14:44044175-44052777 (+)
DBA/2J ENSMUSG00185050151
 protein coding gene Chr14:49103237-49111805 (+)
FVB/NJ ENSMUSG00205031101
 protein coding gene Chr14:43440819-43449387 (+)
JF1/MsJ ENSUMUG00000015834
 protein coding gene Chr14:60342309-60350974 (+)
LP/J ENSMUSG00230052541
 protein coding gene Chr14:61199097-61207699 (+)
NOD/ShiLtJ ENSMUSG00190041714
 protein coding gene Chr14:43801729-43810297 (+)
NZO/HlLtJ ENSMUSG00225044990
 protein coding gene Chr14:51497217-51505819 (+)
PWK/PhJ ENSLUMG00010041247
 protein coding gene Chr14:43266946-43275549 (+)
SPRET/EiJ ENSMSPG00010036113
 protein coding gene Chr14:46664717-46673316 (+)
WSB/EiJ ENSIUOG00005035289
 protein coding gene Chr14:43265677-43274563 (+)



Homology
more
  • Human Ortholog
    NGDN, neuroguidin
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NGDN, neuroguidin
  • Synonyms
    C14orf120, CANu1, LCP5, lpd-2, NGD
  • Links
    NCBI Gene ID: 25983
    UniProt: Q8NEJ9

  • Chr Location
    14q11.2; chr14:23469679-23509862 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    634
  • Tissues
    3
  • cDNA Data
    75
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000022204 Ensembl Gene Model | MGI Sequence Detail 8684 C57BL/6J ±  kb
    transcript ENSMUST00000022815 Ensembl | MGI Sequence Detail 1200 Not Applicable  
    polypeptide ENSMUSP00000022815 Ensembl | MGI Sequence Detail 315 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 76
      cDNA 75
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 3
      Gene Ontology 8
      Phenotypes 14
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory