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Smim11 Gene Detail
Summary
  • Symbol
    Smim11
  • Name
    small integral membrane protein 11
  • Synonyms
    1190017O12Rik, Fam165b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916186
    NCBI Gene: 68936
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:92098174-92109929 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 53.55 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    361 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916186
 protein coding gene Chr16:92098131-92109929 (+)
129S1/SvImJ ENSMUSG00200036784
 protein coding gene Chr16:89027782-89039537 (+)
A/J ENSMUSG00195027341
 protein coding gene Chr16:88785079-88796841 (+)
AKR/J ENSMUSG00220015166
 protein coding gene Chr16:89014764-89026526 (+)
BALB/cJ ENSMUSG00180014084
 protein coding gene Chr16:88859171-88870933 (+)
C3H/HeJ ENSMUSG00175013478
 protein coding gene Chr16:89196443-89208202 (+)
C57BL/6NJ ENSMUSG00215017678
 protein coding gene Chr16:88987428-88999184 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020973
 protein coding gene Chr16:86691448-86703021 (+)
CAST/EiJ ENSTCUG00005018039
 protein coding gene Chr16:88538086-88549833 (+)
CBA/J ENSMUSG00210040071
 protein coding gene Chr16:89102614-89114370 (+)
DBA/2J ENSMUSG00185032223
 protein coding gene Chr16:89047097-89058858 (+)
FVB/NJ ENSMUSG00205021863
 protein coding gene Chr16:88822228-88833988 (+)
JF1/MsJ ENSUMUG00000041741
 protein coding gene Chr16:89185982-89197743 (+)
LP/J ENSMUSG00230032247
 protein coding gene Chr16:91574510-91586265 (+)
NOD/ShiLtJ ENSMUSG00190023165
 protein coding gene Chr16:89012239-89023999 (+)
NZO/HlLtJ ENSMUSG00225030278
 protein coding gene Chr16:94697065-94708826 (+)
PWK/PhJ ENSLUMG00010012681
 protein coding gene Chr16:88814136-88825846 (+)
SPRET/EiJ ENSMSPG00010028022
 protein coding gene Chr16:89954310-89964451 (+)
WSB/EiJ ENSIUOG00005020057
 protein coding gene Chr16:88918784-88930503 (+)



Homology
more
  • Human Ortholog
    SMIM11, small integral membrane protein 11
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SMIM11, small integral membrane protein 11
  • Synonyms
    C21orf51, FAM165B, SMIM11A, SMIM11B
  • Links
    NCBI Gene ID: 54065
    UniProt: P58511

  • Chr Location
    21q22.11; chr21:34375131-34416961 (+)  GRCh38
Human Diseases
less
  • References
    4 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    81 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    804
  • Tissues
    161
  • cDNA Data
    6
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000051989 Ensembl Gene Model | MGI Sequence Detail 11756 C57BL/6J ±  kb
transcript ENSMUST00000063641 Ensembl | MGI Sequence Detail 517 Not Applicable  
polypeptide ENSMUSP00000070724 Ensembl | MGI Sequence Detail 55 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 6
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 107
    Developmental Gene Expression 4
    Diseases 4
    Gene Ontology 1
    Phenotypes 81
  • Earliest
    J:42265 Huang TT, et al., Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts. Arch Biochem Biophys. 1997 Aug 15;344(2):424-32
  • Latest
    J:385727 Harada K, et al., Preventing Differentiation Towards Primitive Macrophages in Stem Cells With Down Syndrome. Immunology. 2026 Mar;177(3):596-612
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory