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Rnf122 Gene Detail
Summary
  • Symbol
    Rnf122
  • Name
    ring finger protein 122
  • Synonyms
    1110063C11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916117
    NCBI Gene: 68867
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:31601848-31621510 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 17.97 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    792 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916117
 protein coding gene Chr8:31601848-31623346 (+)
129S1/SvImJ ENSMUSG00200021515
 protein coding gene Chr8:26682468-26702489 (+)
A/J ENSMUSG00195005077
 protein coding gene Chr8:27175403-27195470 (+)
AKR/J ENSMUSG00220023020
 protein coding gene Chr8:26947063-26967119 (+)
BALB/cJ ENSMUSG00180005446
 protein coding gene Chr8:26722444-26742511 (+)
C3H/HeJ ENSMUSG00175006376
 protein coding gene Chr8:26860766-26880822 (+)
C57BL/6NJ ENSMUSG00215009716
 protein coding gene Chr8:26668574-26688244 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030955
 protein coding gene Chr8:25220610-25240607 (+)
CAST/EiJ ENSTCUG00005020622
 protein coding gene Chr8:26852434-26872622 (+)
CBA/J ENSMUSG00210013378
 protein coding gene Chr8:26704440-26724509 (+)
DBA/2J ENSMUSG00185001864
 protein coding gene Chr8:32635176-32655231 (+)
FVB/NJ ENSMUSG00205003008
 protein coding gene Chr8:25917329-25937394 (+)
JF1/MsJ ENSUMUG00000005603
 protein coding gene Chr8:34329443-34349115 (+)
LP/J ENSMUSG00230014723
 protein coding gene Chr8:36290061-36310243 (+)
NOD/ShiLtJ ENSMUSG00190004415
 protein coding gene Chr8:26746308-26766369 (+)
NZO/HlLtJ ENSMUSG00225021019
 protein coding gene Chr8:39881834-39901496 (+)
PWK/PhJ ENSLUMG00010023187
 protein coding gene Chr8:26603469-26623119 (+)
SPRET/EiJ ENSMSPG00010015421
 protein coding gene Chr8:27281838-27300930 (+)
WSB/EiJ ENSIUOG00005010274
 protein coding gene Chr8:27442368-27462754 (+)



Homology
more
  • Human Ortholog
    RNF122, ring finger protein 122
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RNF122, ring finger protein 122
  • Links
    NCBI Gene ID: 79845
    UniProt: Q9H9V4

  • Chr Location
    8p12; chr8:33547754-33567170 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele display decreased susceptibility to Riboviria infection induced morbidity/mortality with altered expression of interferons and interleukin 6.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    599
  • Tissues
    2
  • cDNA Data
    13
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000039328 Ensembl Gene Model | MGI Sequence Detail 19663 C57BL/6J ±  kb
    transcript ENSMUST00000217278 Ensembl | MGI Sequence Detail 1726 Not Applicable  
    polypeptide ENSMUSP00000150893 Ensembl | MGI Sequence Detail 155 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 3
    References
    more
    • Summaries
      All 30
      Developmental Gene Expression 1
      Gene Ontology 4
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory