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Rab3gap2 Gene Detail
Summary
  • Symbol
    Rab3gap2
  • Name
    RAB3 GTPase activating protein subunit 2
  • Synonyms
    1110059F07Rik, mKIAA0839
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916043
    NCBI Gene: 98732
  • Alliance
    genome feature page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:184936314-185018956 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 89.45 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2359 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916043
 protein coding gene Chr1:184936287-185018956 (+)
129S1/SvImJ ENSMUSG00200021495
 protein coding gene Chr1:182714951-182798498 (+)
A/J ENSMUSG00195041235
 protein coding gene Chr1:182297888-182381669 (+)
AKR/J ENSMUSG00220019336
 protein coding gene Chr1:181524663-181607211 (+)
BALB/cJ ENSMUSG00180032548
 protein coding gene Chr1:182364088-182447888 (+)
C3H/HeJ ENSMUSG00175033256
 protein coding gene Chr1:182539495-182623384 (+)
C57BL/6NJ ENSMUSG00215022699
 protein coding gene Chr1:181752503-181835152 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015020
 protein coding gene Chr1:175067974-175146182 (+)
CAST/EiJ ENSTCUG00005040285
 protein coding gene Chr1:180311505-180393867 (+)
CBA/J ENSMUSG00210018952
 protein coding gene Chr1:182201450-182285150 (+)
DBA/2J ENSMUSG00185033343
 protein coding gene Chr1:186816093-186899797 (+)
FVB/NJ ENSMUSG00205032697
 protein coding gene Chr1:181232190-181315979 (+)
JF1/MsJ ENSUMUG00000003256
 protein coding gene Chr1:185817522-185900037 (+)
LP/J ENSMUSG00230022462
 protein coding gene Chr1:186377860-186462098 (+)
NOD/ShiLtJ ENSMUSG00190028819
 protein coding gene Chr1:182213861-182297588 (+)
NZO/HlLtJ ENSMUSG00225010586
 protein coding gene Chr1:190111101-190193743 (+)
PWK/PhJ ENSLUMG00010015223
 protein coding gene Chr1:181061861-181145637 (+)
SPRET/EiJ ENSMSPG00010021640
 protein coding gene Chr1:184566209-184648354 (+)
WSB/EiJ ENSIUOG00005010311
 protein coding gene Chr1:181407165-181491190 (+)



Homology
more
  • Human Ortholog
    RAB3GAP2, RAB3 GTPase activating non-catalytic protein subunit 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAB3GAP2, RAB3 GTPase activating non-catalytic protein subunit 2
  • Synonyms
    MARTS1, p150, RAB3-GAP150, RAB3GAP150, SPG69, WARBM2
  • Links
    NCBI Gene ID: 25782
    UniProt: Q9H2M9

  • Chr Location
    1q41; chr1:220148293-220272529 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with human RAB3GAP2 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    610
  • Tissues
    13
  • cDNA Data
    13
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000039318 Ensembl Gene Model | MGI Sequence Detail 82643 C57BL/6J ±  kb
    transcript ENSMUST00000069652 Ensembl | MGI Sequence Detail 7052 Not Applicable  
    polypeptide ENSMUSP00000066325 Ensembl | MGI Sequence Detail 1387 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      6 Sequences
    • Protein Ontology
      PR:000013622 Rab3 GTPase-activating protein non-catalytic subunit
      (term hierarchy)
    • InterPro Domains
      IPR026059 Rab3GAP regulatory subunit
      IPR029257 Rab3GAP regulatory subunit, C-terminal
      IPR032839 Rab3-GAP regulatory subunit, N-terminal
    • GlyGen
      Q8BMG7 3 sites, 2 N-linked glycans (2 sites), 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2138353, MGI:2138627
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 13
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory