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Fendrr Gene Detail
Summary
  • Symbol
    Fendrr
  • Name
    Foxf1 adjacent non-coding developmental regulatory RNA
  • Synonyms
    1110050K14Rik, linc-Foxf1a
  • Feature Type
    lncRNA gene
  • IDs
    MGI:1916040
    NCBI Gene: 68790
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:121781621-121809849 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 70.28 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    754 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916040
 lncRNA gene Chr8:121781621-121809849 (-)
129S1/SvImJ ENSMUSG00200043713
 lncRNA gene Chr8:116123428-116151656 (-)
A/J ENSMUSG00195026908
 lncRNA gene Chr8:116408588-116436822 (-)
AKR/J ENSMUSG00220042951
 lncRNA gene Chr8:116598847-116627087 (-)
BALB/cJ ENSMUSG00180029971
 lncRNA gene Chr8:116454368-116482605 (-)
C3H/HeJ ENSMUSG00175031407
 lncRNA gene Chr8:116510718-116538937 (-)
C57BL/6NJ ENSMUSG00215036912
 lncRNA gene Chr8:116084559-116112787 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0006728
 lincRNA gene Chr8:112219952-112248290 (-)
CAST/EiJ ENSTCUG00005037525
 lncRNA gene Chr8:115834234-115862477 (-)
CBA/J ENSMUSG00210037099
 lncRNA gene Chr8:116438009-116466236 (-)
DBA/2J ENSMUSG00185036862
 lncRNA gene Chr8:122542002-122570225 (-)
FVB/NJ ENSMUSG00205039379
 lncRNA gene Chr8:115419045-115447278 (-)
JF1/MsJ ENSUMUG00000036492
 lncRNA gene Chr8:124836207-124864498 (-)
LP/J ENSMUSG00230031755
 lncRNA gene Chr8:126176652-126204876 (-)
NOD/ShiLtJ ENSMUSG00190021350
 lncRNA gene Chr8:116552480-116580706 (-)
NZO/HlLtJ ENSMUSG00225043999
 lncRNA gene Chr8:129542464-129570678 (-)
PWK/PhJ ENSLUMG00010039712
 lncRNA gene Chr8:116257070-116285327 (-)
SPRET/EiJ ENSMSPG00010041412
 lncRNA gene Chr8:118461106-118489667 (-)
WSB/EiJ ENSIUOG00005031873
 lncRNA gene Chr8:117253981-117282189 (-)



Homology
more
  • Human Ortholog
    FENDRR, FOXF1 adjacent non-coding developmental regulatory RNA
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FENDRR, FOXF1 adjacent non-coding developmental regulatory RNA
  • Synonyms
    FOXF1-AS1, FOXF1AS1, lincFOXF1, onco-lncRNA-21, TCONS_00024240
  • Links
    NCBI Gene ID: 400550

  • Chr Location
    16q24.1; chr16:86474525-86509099 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    19 phenotypes from 3 alleles in 3 genetic backgrounds
    1 images
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygotes for a null allele die neonatally with respiratory failure and lung, gastrointestinal tract and heart defects. Homozygotes for another null allele show altered lung lobe development. Chimeric null embryos die during organogenesis with omphalocele and ventricle myocardium hypoplasia.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    673
  • Tissues
    41
  • cDNA Data
    4
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      30
    • RefSeq
      2
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68790 NCBI Gene Model | MGI Sequence Detail 28229 C57BL/6J ±  kb
    transcript NR_130109 RefSeq | MGI Sequence Detail 2714 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 4
      Primer pair 7
      Other 1

      Microarray probesets 1
    References
    more
    • Summaries
      All 19
      Developmental Gene Expression 6
      Phenotypes 4
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:341586 Ali T, et al., Fendrr synergizes with Wnt signalling to regulate fibrosis related genes during lung development via its RNA:dsDNA triplex element. Nucleic Acids Res. 2023 Jul 7;51(12):6227-6237
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory