About   Help   FAQ
Scgb3a1 Gene Detail
Summary
  • Symbol
    Scgb3a1
  • Name
    secretoglobin, family 3A, member 1
  • Synonyms
    1110030K16Rik, HIN-1, LuLeu2, UGRP2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915912
    NCBI Gene: 68662
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
  • Candidate for QTL
    1 QTL
Location &
Maps
more
  • Sequence Map
    Chr11:49554437-49555945 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 29.75 cM, cytoband B1.2
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    123 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915912
 protein coding gene Chr11:49554422-49555945 (+)
129S1/SvImJ ENSMUSG00200038981
 protein coding gene Chr11:46532811-46534319 (+)
A/J ENSMUSG00195030379
 protein coding gene Chr11:46483576-46485084 (+)
AKR/J ENSMUSG00220034047
 protein coding gene Chr11:46670327-46671835 (+)
BALB/cJ ENSMUSG00180033084
 protein coding gene Chr11:46545061-46546569 (+)
C3H/HeJ ENSMUSG00175032486
 protein coding gene Chr11:46515227-46516735 (+)
C57BL/6NJ ENSMUSG00215017382
 protein coding gene Chr11:46442046-46443554 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016276
 protein coding gene Chr11:44546796-44548299 (+)
CAST/EiJ ENSTCUG00005042072
 protein coding gene Chr11:46064061-46065561 (+)
CBA/J ENSMUSG00210027805
 protein coding gene Chr11:46371186-46372694 (+)
DBA/2J ENSMUSG00185026967
 protein coding gene Chr11:46625384-46626892 (+)
FVB/NJ ENSMUSG00205022862
 protein coding gene Chr11:46412976-46414484 (+)
JF1/MsJ ENSUMUG00000032992
 protein coding gene Chr11:46880371-46881877 (+)
LP/J ENSMUSG00230028574
 protein coding gene Chr11:47764540-47766048 (+)
NOD/ShiLtJ ENSMUSG00190034407
 protein coding gene Chr11:46629823-46631331 (+)
NZO/HlLtJ ENSMUSG00225035302
 protein coding gene Chr11:49748844-49750352 (+)
PWK/PhJ ENSLUMG00010029514
 protein coding gene Chr11:46393084-46394638 (+)
SPRET/EiJ ENSMSPG00010016974
 protein coding gene Chr11:47059841-47061340 (+)
WSB/EiJ ENSIUOG00005034344
 protein coding gene Chr11:46428738-46430246 (+)



Homology
more
  • Human Ortholog
    SCGB3A1, secretoglobin family 3A member 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SCGB3A1, secretoglobin family 3A member 1
  • Synonyms
    HIN-1, HIN1, LU105, PnSP-2, UGRP2
  • Links
    NCBI Gene ID: 92304
    UniProt: Q96QR1

  • Chr Location
    5q35.3; chr5:180590105-180591499 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 2 genetic backgrounds
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    14
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    6
  • Gene trapped
    2
  • Targeted
    5
  • Genomic Mutations
    1 involving Scgb3a1
  • Find Mice (IMSR)
    10 strains or lines available
Mice homozygous for a null allele exhibit reduced ciliated cells in the lungs.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    7
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    719
  • Tissues
    56
  • cDNA Data
    17
  • Literature Summary
    12
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000064057 Ensembl Gene Model | MGI Sequence Detail 1509 C57BL/6J ±  kb
transcript ENSMUST00000043873 Ensembl | MGI Sequence Detail 493 Not Applicable  
polypeptide ENSMUSP00000043325 Ensembl | MGI Sequence Detail 104 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 17
    Primer pair 7
    Antibodies 1

    Microarray probesets 3
References
more
  • Summaries
    All 58
    Developmental Gene Expression 12
    Gene Ontology 7
    Phenotypes 19
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:378158 Yokoyama S, et al., Secretoglobin 3A1 in activated muscle satellite cells contributes to myosin heavy chain IIX and IIB fiber differentiation. Cell Mol Life Sci. 2025 Dec 31;83(1):52
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory