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Apool Gene Detail
Summary
  • Symbol
    Apool
  • Name
    apolipoprotein O-like
  • Synonyms
    6720473G16Rik, 9430083G14Rik, E130106L15Rik, Micos27
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915367
    NCBI Gene: 68117
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:111221049-111282452 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 48.76 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1041 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915367
 protein coding gene ChrX:111221031-111282452 (+)
129S1/SvImJ ENSMUSG00200024225
 protein coding gene ChrX:93038155-93099571 (+)
A/J ENSMUSG00195026213
 protein coding gene ChrX:96762385-96823351 (+)
AKR/J ENSMUSG00220013297
 protein coding gene ChrX:90998256-91059669 (+)
BALB/cJ ENSMUSG00180025109
 protein coding gene ChrX:93423972-93484937 (+)
C3H/HeJ ENSMUSG00175027715
 protein coding gene ChrX:97029307-97090268 (+)
C57BL/6NJ ENSMUSG00215013602
 protein coding gene ChrX:93659494-93720913 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033354
 protein coding gene ChrX:105652494-105714960 (+)
CAST/EiJ ENSTCUG00005020628
 protein coding gene ChrX:94363140-94424602 (+)
CBA/J ENSMUSG00210022226
 protein coding gene ChrX:93896211-93957174 (+)
DBA/2J ENSMUSG00185029172
 protein coding gene ChrX:106366209-106427622 (+)
FVB/NJ ENSMUSG00205018086
 protein coding gene ChrX:92974504-93035919 (+)
JF1/MsJ ENSUMUG00000014237
 protein coding gene ChrX:126979670-127040656 (+)
LP/J ENSMUSG00230005210
 protein coding gene ChrX:113003533-113064948 (+)
NOD/ShiLtJ ENSMUSG00190013256
 protein coding gene ChrX:93109278-93170695 (+)
NZO/HlLtJ ENSMUSG00225040195
 protein coding gene ChrX:118156673-118217547 (+)
PWK/PhJ ENSLUMG00010026046
 protein coding gene ChrX:92254157-92315094 (+)
SPRET/EiJ ENSMSPG00010021644
 protein coding gene ChrX:96627987-96685154 (+)
WSB/EiJ ENSIUOG00005014831
 protein coding gene ChrX:93466218-93527645 (+)



Homology
more
  • Human Ortholog
    APOOL, apolipoprotein O like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    APOOL, apolipoprotein O like
  • Synonyms
    CXorf33, FAM121A, Mic27, MICOS27, UNQ8193
  • Links
    NCBI Gene ID: 139322
    UniProt: Q6UXV4

  • Chr Location
    Xq21.1; chrX:85003871-85093315 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 images
    8 phenotype references
Male chimeras hemizygous for a gene trapped allele appear normal at E9.5.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    41
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68117 NCBI Gene Model | MGI Sequence Detail 61404 C57BL/6J ±  kb
transcript NM_026565 RefSeq | MGI Sequence Detail 1357 C57BL/6  
polypeptide Q78IK4 UniProt | EBI | MGI Sequence Detail 265 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000004167 MICOS complex subunit MIC27
    (term hierarchy)
  • InterPro Domains
    IPR019166 MICOS complex subunit MIC26/MIC27
    IPR033182 MICOS complex subunit MIC26/MIC27, animal
  • GlyGen
    Q78IK4 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 46
    cDNA 46

    Microarray probesets 5
Other
Accession IDs
less
MGI:1924328, MGI:1925247
References
more
  • Summaries
    All 38
    Gene Ontology 9
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory