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Chac2 Gene Detail
Summary
  • Symbol
    Chac2
  • Name
    ChaC, cation transport regulator 2
  • Synonyms
    2510006C20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915294
    NCBI Gene: 68044
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:30926707-30936350 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 18.20 cM, cytoband A4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    276 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915294
 protein coding gene Chr11:30926707-30936365 (-)
129S1/SvImJ ENSMUSG00200010068
 protein coding gene Chr11:27960167-27969810 (-)
A/J ENSMUSG00195013650
 protein coding gene Chr11:27895012-27904545 (-)
AKR/J ENSMUSG00220008185
 protein coding gene Chr11:28083523-28093053 (-)
BALB/cJ ENSMUSG00180007548
 protein coding gene Chr11:27894757-27904280 (-)
C3H/HeJ ENSMUSG00175015960
 protein coding gene Chr11:27882164-27891806 (-)
C57BL/6NJ ENSMUSG00215008880
 protein coding gene Chr11:27831582-27841227 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016169
 protein coding gene Chr11:26529624-26539081 (-)
CAST/EiJ ENSTCUG00005026757
 protein coding gene Chr11:27784952-27794745 (-)
CBA/J ENSMUSG00210009661
 protein coding gene Chr11:27852346-27861885 (-)
DBA/2J ENSMUSG00185019034
 protein coding gene Chr11:27981072-27990603 (-)
FVB/NJ ENSMUSG00205020118
 protein coding gene Chr11:27966873-27976400 (-)
JF1/MsJ ENSUMUG00000007296
 protein coding gene Chr11:28207615-28217258 (-)
LP/J ENSMUSG00230014846
 protein coding gene Chr11:29112903-29122690 (-)
NOD/ShiLtJ ENSMUSG00190022668
 protein coding gene Chr11:28098606-28108148 (-)
NZO/HlLtJ ENSMUSG00225030353
 protein coding gene Chr11:31032359-31042163 (-)
PWK/PhJ ENSLUMG00010017073
 protein coding gene Chr11:27853102-27862700 (-)
SPRET/EiJ ENSMSPG00010017798
 protein coding gene Chr11:28247350-28256947 (-)
WSB/EiJ ENSIUOG00005013146
 protein coding gene Chr11:27981967-27991498 (-)



Homology
more
  • Human Ortholog
    CHAC2, ChaC glutathione specific gamma-glutamylcyclotransferase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CHAC2, ChaC glutathione specific gamma-glutamylcyclotransferase 2
  • Synonyms
    GCG1
  • Links
    NCBI Gene ID: 494143
    UniProt: Q8WUX2

  • Chr Location
    2p16.2; chr2:53767783-53775196 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    4
  • Gene trapped
    1
  • Genomic Mutations
    1 involving Chac2
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    11 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    26
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020309 Ensembl Gene Model | MGI Sequence Detail 9644 C57BL/6J ±  kb
transcript ENSMUST00000101394 Ensembl | MGI Sequence Detail 1315 Not Applicable  
polypeptide ENSMUSP00000098942 Ensembl | MGI Sequence Detail 178 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000005399 glutathione-specific gamma-glutamylcyclotransferase 2
    (term hierarchy)
  • EC
    4.3.2.7
  • InterPro Domains
    IPR013024 Gamma-glutamyl cyclotransferase-like
    IPR036568 Gamma-glutamyl cyclotransferase-like superfamily
    IPR006840 Glutathione-specific gamma-glutamylcyclotransferase
Molecular
Reagents
less
  • All nucleic 26
    cDNA 26

    Microarray probesets 2
References
more
  • Summaries
    All 35
    Gene Ontology 8
    Phenotypes 8
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory