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Slc39a10 Gene Detail
Summary
  • Symbol
    Slc39a10
  • Name
    solute carrier family 39 (zinc transporter), member 10
  • Synonyms
    2900042E17Rik, mKIAA1265, Zip10
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914515
    NCBI Gene: 227059
  • Alliance
    genome feature page
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:46846704-46932012 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 24.07 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2324 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914515
 protein coding gene Chr1:46846704-46964952 (-)
129S1/SvImJ ENSMUSG00200001494
 protein coding gene Chr1:44351139-44435605 (-)
A/J ENSMUSG00195001839
 protein coding gene Chr1:44264105-44348584 (-)
AKR/J ENSMUSG00220003147
 protein coding gene Chr1:44058938-44143837 (-)
BALB/cJ ENSMUSG00180002958
 protein coding gene Chr1:44195120-44280436 (-)
C3H/HeJ ENSMUSG00175000057
 protein coding gene Chr1:44294020-44378496 (-)
C57BL/6NJ ENSMUSG00215002960
 protein coding gene Chr1:44170889-44256213 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014134
 protein coding gene Chr1:46636442-46721826 (+)
CAST/EiJ ENSTCUG00005000684
 protein coding gene Chr1:44130082-44214958 (-)
CBA/J ENSMUSG00210027297
 protein coding gene Chr1:43990553-44075028 (-)
DBA/2J ENSMUSG00185029027
 protein coding gene Chr1:45117330-45201807 (-)
FVB/NJ ENSMUSG00205003655
 protein coding gene Chr1:43956842-44041713 (-)
JF1/MsJ ENSUMUG00000001161
 protein coding gene Chr1:44090830-44176465 (-)
LP/J ENSMUSG00230000938
 protein coding gene Chr1:45068389-45153175 (-)
NOD/ShiLtJ ENSMUSG00190002390
 protein coding gene Chr1:44125495-44210385 (-)
NZO/HlLtJ ENSMUSG00225000245
 protein coding gene Chr1:48305926-48390715 (-)
PWK/PhJ ENSLUMG00010002626
 protein coding gene Chr1:43660264-43745170 (-)
SPRET/EiJ ENSMSPG00010012214
 protein coding gene Chr1:45334617-45422930 (-)
WSB/EiJ ENSIUOG00005003376
 protein coding gene Chr1:43760564-43834995 (-)



Homology
more
  • Human Ortholog
    SLC39A10, solute carrier family 39 member 10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC39A10, solute carrier family 39 member 10
  • Synonyms
    LZT-Hs2, ZIP10
  • Links
    NCBI Gene ID: 57181
    UniProt: Q9ULF5

  • Chr Location
    2q32.3; chr2:195575977-195737706 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    31 phenotypes from 2 alleles in 4 genetic backgrounds
    27 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice with conditional loss of function display defects in cellular proliferation and differentiation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    40
  • GO References
    14
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    744
  • Tissues
    36
  • cDNA Data
    12
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000025986 Ensembl Gene Model | MGI Sequence Detail 85309 C57BL/6J ±  kb
    transcript ENSMUST00000027131 Ensembl | MGI Sequence Detail 5498 Not Applicable  
    polypeptide ENSMUSP00000027131 Ensembl | MGI Sequence Detail 833 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 16
      Genomic 1
      cDNA 12
      Primer pair 3
      Antibodies 1

      Microarray probesets 5
    References
    more
    • Summaries
      All 64
      Developmental Gene Expression 6
      Gene Ontology 14
      Phenotypes 27
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:386398 Kageyama A, et al., The oocyte zinc transporter Slc39a10/Zip10 is a regulator of zinc sparks during fertilization in mice. Elife. 2025 Dec 11;14
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory