About   Help   FAQ
Gskip Gene Detail
Summary
  • Symbol
    Gskip
  • Name
    GSK3B interacting protein
  • Synonyms
    4933433P14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914037
    NCBI Gene: 66787
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:105651611-105669317 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 55.92 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    639 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914037
 protein coding gene Chr12:105651088-105669317 (+)
129S1/SvImJ ENSMUSG00200025325
 protein coding gene Chr12:97420980-97439185 (+)
A/J ENSMUSG00195019658
 protein coding gene Chr12:99983018-100001218 (+)
AKR/J ENSMUSG00220038454
 protein coding gene Chr12:97860479-97878685 (+)
BALB/cJ ENSMUSG00180034474
 protein coding gene Chr12:99172254-99190125 (+)
C3H/HeJ ENSMUSG00175029781
 protein coding gene Chr12:101800393-101818594 (+)
C57BL/6NJ ENSMUSG00215039920
 protein coding gene Chr12:98456865-98475068 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018091
 protein coding gene Chr12:100156464-100165261 (+)
CAST/EiJ ENSTCUG00005018305
 protein coding gene Chr12:97910585-97928070 (+)
CBA/J ENSMUSG00210013880
 protein coding gene Chr12:98862392-98880590 (+)
DBA/2J ENSMUSG00185042097
 protein coding gene Chr12:100628052-100646250 (+)
FVB/NJ ENSMUSG00205014109
 protein coding gene Chr12:97857757-97875627 (+)
JF1/MsJ ENSUMUG00000013377
 protein coding gene Chr12:105398022-105415431 (+)
LP/J ENSMUSG00230026033
 protein coding gene Chr12:107686273-107704477 (+)
NOD/ShiLtJ ENSMUSG00190026178
 protein coding gene Chr12:87334760-87352948 (-)
NZO/HlLtJ ENSMUSG00225037049
 protein coding gene Chr12:109427345-109445212 (+)
PWK/PhJ ENSLUMG00010013062
 protein coding gene Chr12:98863525-98881281 (+)
SPRET/EiJ ENSMSPG00010017406
 protein coding gene Chr12:101160146-101177839 (+)
WSB/EiJ ENSIUOG00005008580
 protein coding gene Chr12:97864917-97882566 (+)



Homology
more
  • Human Ortholog
    GSKIP, GSK3B interacting protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GSKIP, GSK3B interacting protein
  • Synonyms
    C14orf129, HSPC210
  • Links
    NCBI Gene ID: 51527
    UniProt: Q9P0R6

  • Chr Location
    14q32.2; chr14:96363452-96387290 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit partial lethality between E16.5 and E1.5, complete lethality at birth, cyanosis, primary atelectasis resulting in respiratory failure and cleft secondary palate due to delayed ossification in the upper jaw.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    35
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    711
  • Tissues
    24
  • cDNA Data
    13
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66787 NCBI Gene Model | MGI Sequence Detail 17707 C57BL/6J ±  kb
    transcript NM_178613 RefSeq | MGI Sequence Detail 2787 C57BL/6  
    polypeptide Q8BGR8 UniProt | EBI | MGI Sequence Detail 139 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 14
      Primer pair 1
      Antibodies 1

      Microarray probesets 7
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 2
      Gene Ontology 7
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:320198 Sakai SS, et al., Loss of Atg2b and Gskip Impairs the Maintenance of the Hematopoietic Stem Cell Pool Size. Mol Cell Biol. 2022 Jan 20;42(1):e0002421
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory