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Mat2b Gene Detail
Summary
  • Symbol
    Mat2b
  • Name
    methionine adenosyltransferase 2 non-catalytic beta subunit methionine
  • Synonyms
    1110064C04Rik, 2410018D16Rik, MATIIbeta
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913667
    NCBI Gene: 108645
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:40570141-40586030 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 24.40 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    519 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913667
 protein coding gene Chr11:40570141-40586030 (-)
129S1/SvImJ ENSMUSG00200006728
 protein coding gene Chr11:37678697-37694589 (-)
A/J ENSMUSG00195006904
 protein coding gene Chr11:37592068-37607960 (-)
AKR/J ENSMUSG00220003152
 protein coding gene Chr11:37782001-37797895 (-)
BALB/cJ ENSMUSG00180001688
 protein coding gene Chr11:37589114-37605007 (-)
C3H/HeJ ENSMUSG00175003717
 protein coding gene Chr11:37581718-37597610 (-)
C57BL/6NJ ENSMUSG00215009349
 protein coding gene Chr11:37496909-37512801 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016211
 protein coding gene Chr11:36077184-36093143 (-)
CAST/EiJ ENSTCUG00005012875
 protein coding gene Chr11:37344328-37360147 (-)
CBA/J ENSMUSG00210006755
 protein coding gene Chr11:37477015-37492907 (-)
DBA/2J ENSMUSG00185010179
 protein coding gene Chr11:37620430-37636321 (-)
FVB/NJ ENSMUSG00205011897
 protein coding gene Chr11:37618749-37634643 (-)
JF1/MsJ ENSUMUG00000005113
 protein coding gene Chr11:37897264-37913082 (-)
LP/J ENSMUSG00230002867
 protein coding gene Chr11:38809277-38825169 (-)
NOD/ShiLtJ ENSMUSG00190007317
 protein coding gene Chr11:37682820-37698711 (-)
NZO/HlLtJ ENSMUSG00225035312
 protein coding gene Chr11:40725269-40741158 (-)
PWK/PhJ ENSLUMG00010007226
 protein coding gene Chr11:37481703-37497524 (-)
SPRET/EiJ ENSMSPG00010002242
 protein coding gene Chr11:38004206-38020134 (-)
WSB/EiJ ENSIUOG00005002040
 protein coding gene Chr11:37524856-37540748 (-)



Homology
more
  • Human Ortholog
    MAT2B, methionine adenosyltransferase 2 non-catalytic beta subunit
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAT2B, methionine adenosyltransferase 2 non-catalytic beta subunit
  • Synonyms
    MAT-II, MATIIbeta, Nbla02999, SDR23E1, TGR
  • Links
    NCBI Gene ID: 27430
    UniProt: Q9NZL9

  • Chr Location
    5q34; chr5:163503064-163519558 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    792
  • Tissues
    126
  • cDNA Data
    183
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 108645 NCBI Gene Model | MGI Sequence Detail 15890 C57BL/6J ±  kb
transcript NM_001199274 RefSeq | MGI Sequence Detail 2066 Not Specified  
polypeptide Q99LB6 UniProt | EBI | MGI Sequence Detail 334 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000010203 methionine adenosyltransferase 2 subunit beta
    (term hierarchy)
  • InterPro Domains
    IPR005913 dTDP-4-dehydrorhamnose reductase
    IPR036291 NAD(P)-binding domain superfamily
    IPR029903 RmlD-like, substrate binding domain
  • GlyGen
    Q99LB6 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 191
    cDNA 184
    Primer pair 7
    Antibodies 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:1916131, MGI:2144077, MGI:2144417
References
more
  • Summaries
    All 51
    Developmental Gene Expression 7
    Gene Ontology 6
    Phenotypes 13
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:312368 Imbard A, et al., Liver and brain differential expression of one-carbon metabolism genes during ontogenesis. Sci Rep. 2021 Oct 26;11(1):21132
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory