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Mrpl54 Gene Detail
Summary
  • Symbol
    Mrpl54
  • Name
    mitochondrial ribosomal protein L54
  • Synonyms
    0610008M19Rik, D10Sut1e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913297
    NCBI Gene: 66047
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:81100556-81102760 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM, cytoband C1
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    109 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913297
 protein coding gene Chr10:81100547-81102768 (-)
129S1/SvImJ ENSMUSG00200044162
 protein coding gene Chr10:77727690-77729911 (-)
A/J ENSMUSG00195049124
 protein coding gene Chr10:78122960-78125181 (-)
AKR/J ENSMUSG00220046823
 protein coding gene Chr10:77720648-77722870 (-)
BALB/cJ ENSMUSG00180052201
 protein coding gene Chr10:78133413-78135634 (-)
C3H/HeJ ENSMUSG00175049691
 protein coding gene Chr10:78004166-78006387 (-)
C57BL/6NJ ENSMUSG00215052307
 protein coding gene Chr10:77746025-77748246 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015629
 protein coding gene Chr10:75265256-75267484 (-)
CAST/EiJ ENSTCUG00005051369
 protein coding gene Chr10:77627513-77629748 (-)
CBA/J ENSMUSG00210049069
 protein coding gene Chr10:77860192-77862413 (-)
DBA/2J ENSMUSG00185046461
 protein coding gene Chr10:78202625-78204846 (-)
FVB/NJ ENSMUSG00205029375
 protein coding gene Chr10:77915439-77917661 (-)
JF1/MsJ ENSUMUG00000020466
 protein coding gene Chr10:79429997-79432227 (-)
LP/J ENSMUSG00230050663
 protein coding gene Chr10:79972209-79974430 (-)
NOD/ShiLtJ ENSMUSG00190043266
 protein coding gene Chr10:78116324-78118545 (-)
NZO/HlLtJ ENSMUSG00225052540
 protein coding gene Chr10:84258778-84260999 (-)
PWK/PhJ ENSLUMG00010044656
 protein coding gene Chr10:77793681-77795911 (-)
SPRET/EiJ ENSMSPG00010031535
 protein coding gene Chr10:79403865-79406115 (-)
WSB/EiJ ENSIUOG00005050109
 protein coding gene Chr10:77856390-77858604 (-)



Homology
more
  • Human Ortholog
    MRPL54, mitochondrial ribosomal protein L54
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPL54, mitochondrial ribosomal protein L54
  • Synonyms
    L54mt, mL54, MRP-L54
  • Links
    NCBI Gene ID: 116541
    UniProt: Q6P161

  • Chr Location
    19p13.3; chr19:3762672-3768575 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    740
  • Tissues
    34
  • cDNA Data
    44
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66047 NCBI Gene Model | MGI Sequence Detail 2205 C57BL/6J ±  kb
transcript NM_025317 RefSeq | MGI Sequence Detail 587 ZRU/MplStud  
polypeptide Q9CPW3 UniProt | EBI | MGI Sequence Detail 135 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 47
    cDNA 44
    Primer pair 3

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-36571, MGI:107991
References
more
  • Summaries
    All 55
    Developmental Gene Expression 7
    Gene Ontology 8
    Phenotypes 16
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:381044 Spaan CN, et al., Reduced levels of mitochondrial ribosomal protein MRPL54 does not alter Apc related adenoma formation. PLoS One. 2026;21(3):e0344161
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory