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Phyhip Gene Detail
Summary
  • Symbol
    Phyhip
  • Name
    phytanoyl-CoA hydroxylase interacting protein
  • Synonyms
    C630010D02Rik, PAHX-AP#1, PAHX-AP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860417
    NCBI Gene: 105653
  • Alliance
    genome feature page
  • Transcription Start Sites
    20 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:70694957-70706266 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 36.32 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    296 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1860417
 protein coding gene Chr14:70694916-70706272 (+)
129S1/SvImJ ENSMUSG00200028504
 protein coding gene Chr14:59087476-59098707 (+)
A/J ENSMUSG00195012936
 protein coding gene Chr14:59267961-59279319 (+)
AKR/J ENSMUSG00220027407
 protein coding gene Chr14:58603684-58615041 (+)
BALB/cJ ENSMUSG00180032141
 protein coding gene Chr14:58876519-58887878 (+)
C3H/HeJ ENSMUSG00175034860
 protein coding gene Chr14:60637005-60648373 (+)
C57BL/6NJ ENSMUSG00215021954
 protein coding gene Chr14:58813209-58824566 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019482
 protein coding gene Chr14:61560901-61572427 (+)
CAST/EiJ ENSTCUG00005038530
 protein coding gene Chr14:60518077-60529439 (+)
CBA/J ENSMUSG00210036170
 protein coding gene Chr14:59252829-59264185 (+)
DBA/2J ENSMUSG00185023021
 protein coding gene Chr14:64422422-64433779 (+)
FVB/NJ ENSMUSG00205033116
 protein coding gene Chr14:58763114-58774471 (+)
JF1/MsJ ENSUMUG00000036897
 protein coding gene Chr14:75598393-75609623 (+)
LP/J ENSMUSG00230012491
 protein coding gene Chr14:76451242-76462472 (+)
NOD/ShiLtJ ENSMUSG00190029850
 protein coding gene Chr14:59047968-59059324 (+)
NZO/HlLtJ ENSMUSG00225039503
 protein coding gene Chr14:66774805-66786161 (+)
PWK/PhJ ENSLUMG00010035026
 protein coding gene Chr14:58449561-58460849 (+)
SPRET/EiJ ENSMSPG00010026861
 protein coding gene Chr14:62010987-62022316 (+)
WSB/EiJ ENSIUOG00005038081
 protein coding gene Chr14:58491069-58502412 (+)



Homology
more
  • Human Ortholog
    PHYHIP, phytanoyl-CoA 2-hydroxylase interacting protein
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PHYHIP, phytanoyl-CoA 2-hydroxylase interacting protein
  • Synonyms
    DYRK1AP3, PAHX-AP, PAHXAP1
  • Links
    NCBI Gene ID: 9796
    UniProt: Q92561

  • Chr Location
    8p21.3; chr8:22219703-22232101 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    770
  • Tissues
    44
  • cDNA Data
    4
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 105653 NCBI Gene Model | MGI Sequence Detail 11310 C57BL/6J ±  kb
transcript NM_145981 RefSeq | MGI Sequence Detail 2789 C57BL/6  
polypeptide Q8K0S0 UniProt | EBI | MGI Sequence Detail 330 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000012676 phytanoyl-CoA hydroxylase-interacting protein
    (term hierarchy)
  • InterPro Domains
    IPR003961 Fibronectin type III
    IPR036116 Fibronectin type III superfamily
    IPR013783 Immunoglobulin-like fold
    IPR042868 Phytanoyl-CoA hydroxylase-interacting protein-like
    IPR045545 Phytanoyl-CoA hydroxylase-interacting protein-like, C-terminal
  • GlyGen
    Q8K0S0 2 sites, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5
    Antibodies 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2145792
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:60726 Lee ZH, et al., Identification of a brain specific protein that associates with a refsum disease gene product, phytanoyl-CoA alpha-hydroxylase. Brain Res Mol Brain Res. 2000 Feb 22;75(2):237-47
  • Latest
    J:336825 Raspa M, et al., Dry ice is a reliable substrate for the distribution of frozen mouse spermatozoa: A multi-centric study. Theriogenology. 2017 Jul 1;96:49-57
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory