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Slc27a2 Gene Detail
Summary
  • Symbol
    Slc27a2
  • Name
    solute carrier family 27 (fatty acid transporter), member 2
  • Synonyms
    ACSVL1, FATP2, FATP2, Vlac, Vlacs, VLCS
  • Feature Type
    protein coding gene
  • IDs
    MGI:1347099
    NCBI Gene: 26458
  • Alliance
    genome feature page
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:126394944-126430163 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 61.76 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1077 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1347099
 protein coding gene Chr2:126394327-126430163 (+)
129S1/SvImJ ENSMUSG00200044347
 protein coding gene Chr2:123447798-123490074 (+)
A/J ENSMUSG00195029599
 protein coding gene Chr2:123468242-123510505 (+)
AKR/J ENSMUSG00220044248
 protein coding gene Chr2:123234014-123276296 (+)
BALB/cJ ENSMUSG00180046287
 protein coding gene Chr2:123255174-123297442 (+)
C3H/HeJ ENSMUSG00175038198
 protein coding gene Chr2:123797325-123833189 (+)
C57BL/6NJ ENSMUSG00215017473
 protein coding gene Chr2:123315576-123351419 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024238
 protein coding gene Chr2:119244402-119280783 (+)
CAST/EiJ ENSTCUG00005033072
 protein coding gene Chr2:122605755-122641604 (+)
CBA/J ENSMUSG00210031123
 protein coding gene Chr2:123645798-123681658 (+)
DBA/2J ENSMUSG00185029629
 protein coding gene Chr2:123299815-123335678 (+)
FVB/NJ ENSMUSG00205023283
 protein coding gene Chr2:122470807-122513093 (+)
JF1/MsJ ENSUMUG00000010570
 protein coding gene Chr2:123158413-123194275 (+)
LP/J ENSMUSG00230035167
 protein coding gene Chr2:125083246-125125528 (+)
NOD/ShiLtJ ENSMUSG00190013380
 protein coding gene Chr2:123441039-123483316 (+)
NZO/HlLtJ ENSMUSG00225026543
 protein coding gene Chr2:132989389-133031670 (+)
PWK/PhJ ENSLUMG00010045026
 protein coding gene Chr2:123047236-123083169 (+)
SPRET/EiJ ENSMSPG00010028929
 protein coding gene Chr2:125483418-125521799 (+)
WSB/EiJ ENSIUOG00005037494
 protein coding gene Chr2:123249240-123285179 (+)



Homology
more
  • Human Ortholog
    SLC27A2, solute carrier family 27 member 2
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC27A2, solute carrier family 27 member 2
  • Synonyms
    ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS
  • Links
    NCBI Gene ID: 11001
    UniProt: O14975

  • Chr Location
    15q21.2; chr15:50182196-50236445 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutant mice are viable and show no gross morphological abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    80
  • GO References
    16
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    970
  • Tissues
    262
  • cDNA Data
    175
  • Literature Summary
    15
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 26458 NCBI Gene Model | MGI Sequence Detail 35220 C57BL/6J ±  kb
transcript NM_011978 RefSeq | MGI Sequence Detail 2309 C57BL/6  
polypeptide O35488 UniProt | EBI | MGI Sequence Detail 620 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 179
    cDNA 175
    Primer pair 3
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1330825
References
more
  • Summaries
    All 70
    Developmental Gene Expression 15
    Gene Ontology 16
    Phenotypes 19
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:367303 He X, et al., Mechanism of valproic acid-induced hepatic steatosis via enhancing NRF2-FATP2-mediated fatty acid uptake. Theranostics. 2025;15(11):5258-5276
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory