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Farsb Gene Detail
Summary
  • Symbol
    Farsb
  • Name
    phenylalanyl-tRNA synthetase, beta subunit
  • Synonyms
    Farsl, Farslb, Frsb, PheRS alpha
  • Feature Type
    protein coding gene
  • IDs
    MGI:1346035
    NCBI Gene: 23874
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:78394612-78465534 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 40.44 cM, cytoband C4
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    428 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1346035
 protein coding gene Chr1:78394593-78465534 (-)
129S1/SvImJ ENSMUSG00200033837
 protein coding gene Chr1:76075449-76146890 (-)
A/J ENSMUSG00195008058
 protein coding gene Chr1:75485313-75556238 (-)
AKR/J ENSMUSG00220010107
 protein coding gene Chr1:75637140-75708074 (-)
BALB/cJ ENSMUSG00180015970
 protein coding gene Chr1:75747909-75818834 (-)
C3H/HeJ ENSMUSG00175016724
 protein coding gene Chr1:75890201-75961119 (-)
C57BL/6NJ ENSMUSG00215024786
 protein coding gene Chr1:75795620-75866546 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014310
 protein coding gene Chr1:71807400-71881653 (-)
CAST/EiJ ENSTCUG00005028487
 protein coding gene Chr1:75494379-75565950 (-)
CBA/J ENSMUSG00210040391
 protein coding gene Chr1:75617833-75688754 (-)
DBA/2J ENSMUSG00185028089
 protein coding gene Chr1:76670286-76741217 (-)
FVB/NJ ENSMUSG00205027507
 protein coding gene Chr1:75202847-75274297 (-)
JF1/MsJ ENSUMUG00000005771
 protein coding gene Chr1:75543367-75614786 (-)
LP/J ENSMUSG00230012202
 protein coding gene Chr1:76651039-76722475 (-)
NOD/ShiLtJ ENSMUSG00190036098
 protein coding gene Chr1:75818022-75888952 (-)
NZO/HlLtJ ENSMUSG00225038904
 protein coding gene Chr1:79870086-79941536 (-)
PWK/PhJ ENSLUMG00010013535
 protein coding gene Chr1:75143529-75214832 (-)
SPRET/EiJ ENSMSPG00010019379
 protein coding gene Chr1:77289049-77353422 (-)
WSB/EiJ ENSIUOG00005013202
 protein coding gene Chr1:75414725-75485667 (-)



Homology
more
  • Human Ortholog
    FARSB, phenylalanyl-tRNA synthetase subunit beta
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FARSB, phenylalanyl-tRNA synthetase subunit beta
  • Synonyms
    FARSLB, FRSB, HSPC173, NEDBLLA, PheHB, PheRS, RILDBC, RILDBC1, RJBS
  • Links
    NCBI Gene ID: 10056
    UniProt: Q9NSD9

  • Chr Location
    2q36.1; chr2:222566899-222656313 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    34
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    909
  • Tissues
    121
  • cDNA Data
    18
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026245 Ensembl Gene Model | MGI Sequence Detail 70923 C57BL/6J ±  kb
transcript ENSMUST00000170217 Ensembl | MGI Sequence Detail 2036 Not Applicable  
polypeptide ENSMUSP00000129828 Ensembl | MGI Sequence Detail 589 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    10 Sequences
  • Protein Ontology
    PR:000007347 eukaryotic-type phenylalanine--tRNA ligase beta subunit
    (term hierarchy)
  • EC
    6.1.1.20
  • InterPro Domains
    IPR005146 B3/B4 tRNA-binding domain
    IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)
    IPR040659 Phenylalanine--tRNA ligase beta subunit, B1 domain
    IPR045060 Phenylalanine-tRNA ligase, class IIc, beta subunit
    IPR041616 Phenylalanyl tRNA synthetase beta chain, core domain
    IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archaeal/eukaryotic type
    IPR020825 Phenylalanyl-tRNA synthetase-like, B3/B4
    IPR009061 Putative DNA-binding domain superfamily
    IPR005147 tRNA synthetase, B5-domain
  • GlyGen
    Q9WUA2 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 18
    cDNA 18

    Microarray probesets 4
Other
Accession IDs
less
MGI:2138654
References
more
  • Summaries
    All 47
    Developmental Gene Expression 3
    Gene Ontology 9
    Phenotypes 12
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory