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Slc29a2 Gene Detail
Summary
  • Symbol
    Slc29a2
  • Name
    solute carrier family 29 (nucleoside transporters), member 2
  • Synonyms
    Der12, ENT2, HNP36
  • Feature Type
    protein coding gene
  • IDs
    MGI:1345278
    NCBI Gene: 13340
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:5073888-5082000 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 4.23 cM, cytoband A
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    289 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1345278
 protein coding gene Chr19:5069085-5082000 (+)
129S1/SvImJ ENSMUSG00200051698
 protein coding gene Chr19:1834250-1842360 (+)
A/J ENSMUSG00195052450
 protein coding gene Chr19:2229770-2237890 (+)
AKR/J ENSMUSG00220042622
 protein coding gene Chr19:2002848-2010966 (+)
BALB/cJ ENSMUSG00180048884
 protein coding gene Chr19:2604494-2612612 (+)
C3H/HeJ ENSMUSG00175009388
 protein coding gene Chr19:1849217-1857335 (+)
C57BL/6NJ ENSMUSG00215036389
 protein coding gene Chr19:2072426-2080540 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022528
 protein coding gene Chr19:1777665-1785818 (+)
CAST/EiJ ENSTCUG00005026044
 protein coding gene Chr19:1993087-2001190 (+)
CBA/J ENSMUSG00210044061
 protein coding gene Chr19:1853067-1861185 (+)
DBA/2J ENSMUSG00185045311
 protein coding gene Chr19:2229539-2237653 (+)
FVB/NJ ENSMUSG00205043728
 protein coding gene Chr19:2232781-2240874 (+)
JF1/MsJ ENSUMUG00000048751
 protein coding gene Chr19:2212607-2220744 (+)
LP/J ENSMUSG00230052326
 protein coding gene Chr19:3141198-3149308 (+)
NOD/ShiLtJ ENSMUSG00190048216
 protein coding gene Chr19:1764261-1772379 (+)
NZO/HlLtJ ENSMUSG00225025527
 protein coding gene Chr19:6849946-6858056 (+)
PWK/PhJ ENSLUMG00010006533
 protein coding gene Chr19:1985173-1993292 (+)
SPRET/EiJ ENSMSPG00010045263
 protein coding gene Chr19:1976152-1984336 (+)
WSB/EiJ ENSIUOG00005042912
 protein coding gene Chr19:1864291-1872382 (+)



Homology
more
  • Human Ortholog
    SLC29A2, solute carrier family 29 member 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC29A2, solute carrier family 29 member 2
  • Synonyms
    DER12, ENT2, hENT2, HNP36
  • Links
    NCBI Gene ID: 3177
    UniProt: Q14542

  • Chr Location
    11q13.2; chr11:66362520-66372476 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap allele exhibit normal adenosine uptake in erythrocytes and protection from acute lung injury.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    122
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    598
  • Tissues
    1
  • cDNA Data
    28
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024891 Ensembl Gene Model | MGI Sequence Detail 8113 C57BL/6J ±  kb
transcript ENSMUST00000236152 Ensembl | MGI Sequence Detail 2619 Not Applicable  
polypeptide ENSMUSP00000157780 Ensembl | MGI Sequence Detail 456 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 31
    cDNA 30
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-24063, MGI:103195
References
more
  • Summaries
    All 56
    Developmental Gene Expression 2
    Gene Ontology 10
    Phenotypes 10
  • Earliest
    J:27223 Lanahan A, et al., Growth factor-induced delayed early response genes. Mol Cell Biol. 1992 Sep;12(9):3919-29
  • Latest
    J:378285 Chen CY, et al., Deletion of equilibrative nucleoside transporter 2 disturbs energy metabolism and exacerbates disease progression in an experimental model of Huntington's disease. Neurobiol Dis. 2023 Feb;177:106004
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory