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Ndufc2 Gene Detail
Summary
  • Symbol
    Ndufc2
  • Name
    NADH:ubiquinone oxidoreductase subunit C2
  • Synonyms
    14.5b subunit of the NADH-ubiquinone dehydrogenase complex, 1810004I06Rik, 2010300P09Rik, G1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1344370
    NCBI Gene: 68197
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:97049210-97057007 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 53.49 cM, cytoband E3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    421 from dbSNP Build 142
  • Strain Annotations
    28
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1344370
 protein coding gene Chr7:97049210-97057009 (+)
129S1/SvImJ ENSMUSG00200052822
 protein coding gene Chr15:76853888-76858021 (+)
129S1/SvImJ ENSMUSG00200046659
 protein coding gene Chr7:83872064-83879961 (+)
A/J ENSMUSG00195046181
 protein coding gene Chr15:76796906-76801039 (+)
A/J ENSMUSG00195036595
 protein coding gene Chr7:88377006-88384905 (+)
AKR/J ENSMUSG00220047085
 protein coding gene Chr7:81794270-81802169 (+)
AKR/J ENSMUSG00220049747
 protein coding gene Chr15:76840338-76844473 (+)
BALB/cJ ENSMUSG00180034324
 protein coding gene Chr7:85050410-85058307 (+)
BALB/cJ ENSMUSG00180048441
 protein coding gene Chr15:76673944-76678077 (+)
C3H/HeJ ENSMUSG00175049390
 protein coding gene Chr15:76988637-76989267 (+)
C3H/HeJ ENSMUSG00175021721
 protein coding gene Chr7:85700910-85708700 (+)
C57BL/6NJ ENSMUSG00215012140
 protein coding gene Chr7:84890137-84897936 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030001
 protein coding gene Chr7:100066349-100074502 (+)
CAST/EiJ ENSTCUG00005027980
 protein coding gene Chr7:88264161-88271941 (+)
CBA/J ENSMUSG00210025082
 protein coding gene Chr7:85548934-85556719 (+)
CBA/J ENSMUSG00210043046
 protein coding gene Chr15:76763779-76764409 (+)
DBA/2J ENSMUSG00185029705
 protein coding gene Chr7:89875629-89883422 (+)
DBA/2J ENSMUSG00185039513
 protein coding gene Chr15:76773665-76774295 (+)
FVB/NJ ENSMUSG00205020640
 protein coding gene Chr7:85551623-85559521 (+)
FVB/NJ ENSMUSG00205043494
 protein coding gene Chr15:76497481-76501614 (+)
JF1/MsJ ENSUMUG00000045756
 protein coding gene Chr7:94775562-94783355 (+)
LP/J ENSMUSG00230050623
 protein coding gene Chr15:80102310-80106443 (+)
LP/J ENSMUSG00230037241
 protein coding gene Chr7:95989127-95997029 (+)
NOD/ShiLtJ ENSMUSG00190020712
 protein coding gene Chr7:85818255-85826155 (+)
NOD/ShiLtJ ENSMUSG00190051131
 protein coding gene Chr15:76779764-76783897 (+)
NZO/HlLtJ ENSMUSG00225048516
 protein coding gene Chr7:94177129-94185683 (+)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010011737
 protein coding gene Chr7:85218573-85226351 (+)
WSB/EiJ ENSIUOG00005009960
 protein coding gene Chr7:86159852-86167713 (+)



Homology
more
  • Human Ortholog
    NDUFC2, NADH:ubiquinone oxidoreductase subunit C2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NDUFC2, NADH:ubiquinone oxidoreductase subunit C2
  • Synonyms
    B14.5b, CI-B14.5b, HLC-1, MC1DN36, NADHDH2
  • Links
    NCBI Gene ID: 4718
    UniProt: O95298

  • Chr Location
    11q14.1; chr11:78068297-78081871 (-)  GRCh38
  • Human Ortholog
    NDUFC2-KCTD14, NDUFC2-KCTD14 readthrough
  • Links
    NCBI Gene ID: 100532726
    UniProt: E9PQ53

  • Chr Location
    11q14.1; chr11:78015715-78079865 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with human NDUFC2 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    32 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • Tissues
    102
  • cDNA Data
    146
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68197 NCBI Gene Model | MGI Sequence Detail 7798 C57BL/6J ±  kb
transcript NM_024220 RefSeq | MGI Sequence Detail 693 C57BL/6  
polypeptide Q9CQ54 UniProt | EBI | MGI Sequence Detail 120 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 146
    cDNA 146

    Microarray probesets 5
Other
Accession IDs
less
MGI:1915447, MGI:1919437, MGI:2144702
References
more
  • Summaries
    All 71
    Developmental Gene Expression 4
    Gene Ontology 11
    Phenotypes 32
  • Earliest
    J:141526 Russell LB, et al., Analysis of the albino-locus region of the mouse. III. Time of death of prenatal lethals. Genetics. 1979 May;92(1):205-13
  • Latest
    J:355679 Vercellino I, et al., SCAF1 drives the compositional diversity of mammalian respirasomes. Nat Struct Mol Biol. 2024 Jul;31(7):1061-1071
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory