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Ccnt1 Gene Detail
Summary
  • Symbol
    Ccnt1
  • Name
    cyclin T1
  • Synonyms
    2810478G24Rik, CycT1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1328363
    NCBI Gene: 12455
  • Alliance
    genome feature page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:98436570-98468340 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 54.54 cM, cytoband F2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    844 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1328363
 protein coding gene Chr15:98436570-98468804 (-)
129S1/SvImJ ENSMUSG00200049657
 protein coding gene Chr15:95624173-95656565 (-)
A/J ENSMUSG00195040363
 protein coding gene Chr15:95497676-95530089 (-)
AKR/J ENSMUSG00220044742
 protein coding gene Chr15:95509738-95542134 (-)
BALB/cJ ENSMUSG00180043255
 protein coding gene Chr15:95411780-95444241 (-)
C3H/HeJ ENSMUSG00175035090
 protein coding gene Chr15:95677854-95710262 (-)
C57BL/6NJ ENSMUSG00215050509
 protein coding gene Chr15:95474622-95506861 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020236
 protein coding gene Chr15:92233837-92270327 (-)
CAST/EiJ ENSTCUG00005042916
 protein coding gene Chr15:94948639-94981168 (-)
CBA/J ENSMUSG00210027630
 protein coding gene Chr15:95469311-95501700 (-)
DBA/2J ENSMUSG00185041253
 protein coding gene Chr15:95504274-95536771 (-)
FVB/NJ ENSMUSG00205031499
 protein coding gene Chr15:95209807-95242045 (-)
JF1/MsJ ENSUMUG00000032354
 protein coding gene Chr15:94983259-95015717 (-)
LP/J ENSMUSG00230036308
 protein coding gene Chr15:98847917-98880313 (-)
NOD/ShiLtJ ENSMUSG00190041511
 protein coding gene Chr15:95489723-95521956 (-)
NZO/HlLtJ ENSMUSG00225041480
 protein coding gene Chr15:99111654-99143885 (-)
PWK/PhJ ENSLUMG00010042356
 protein coding gene Chr15:95180627-95212868 (-)
SPRET/EiJ ENSMSPG00010047757
 protein coding gene Chr15:97006800-97030847 (-)
WSB/EiJ ENSIUOG00005031135
 protein coding gene Chr15:95601352-95633842 (-)



Homology
more
  • Human Ortholog
    CCNT1, cyclin T1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCNT1, cyclin T1
  • Synonyms
    CCNT, CYCT1, HIVE1
  • Links
    NCBI Gene ID: 904
    UniProt: O60563

  • Chr Location
    12q13.11-q13.12; chr12:48688458-48716998 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 2 alleles in 2 genetic backgrounds
    35 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a hypomorphic allele do not express AIRE-responsive genes in the thymus and display lymphocytic infiltration of lacrimal and salivary glands.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    53
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    686
  • Tissues
    66
  • cDNA Data
    17
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12455 NCBI Gene Model | MGI Sequence Detail 31771 C57BL/6J ±  kb
    transcript NM_009833 RefSeq | MGI Sequence Detail 6796 C57BL/6  
    polypeptide Q9QWV9 UniProt | EBI | MGI Sequence Detail 724 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 17
      Antibodies 2

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1920080, MGI:2145948
    References
    more
    • Summaries
      All 95
      Developmental Gene Expression 7
      Diseases 1
      Gene Ontology 13
      Phenotypes 35
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory