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Per3 Gene Detail
Summary
  • Symbol
    Per3
  • Name
    period circadian clock 3
  • Synonyms
    2810049O06Rik, mPer3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1277134
    NCBI Gene: 18628
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:151088109-151129122 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 81.53 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    455 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1277134
 protein coding gene Chr4:151081475-151129167 (-)
129S1/SvImJ ENSMUSG00200018819
 protein coding gene Chr4:142150979-142191887 (-)
A/J ENSMUSG00195014728
 protein coding gene Chr4:143787301-143828315 (-)
AKR/J ENSMUSG00220023709
 protein coding gene Chr4:143372864-143413881 (-)
BALB/cJ ENSMUSG00180002265
 protein coding gene Chr4:141469839-141510855 (-)
C3H/HeJ ENSMUSG00175017266
 protein coding gene Chr4:144753135-144794161 (-)
C57BL/6NJ ENSMUSG00215007207
 protein coding gene Chr4:143598309-143639326 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026837
 protein coding gene Chr4:140895155-140936433 (-)
CAST/EiJ ENSTCUG00005027612
 protein coding gene Chr4:147460491-147501525 (-)
CBA/J ENSMUSG00210004597
 protein coding gene Chr4:143404760-143445785 (-)
DBA/2J ENSMUSG00185014018
 protein coding gene Chr4:146970890-147011882 (-)
FVB/NJ ENSMUSG00205037463
 protein coding gene Chr4:141867326-141908319 (-)
JF1/MsJ ENSUMUG00000003815
 protein coding gene Chr4:149972904-150014049 (-)
LP/J ENSMUSG00230019648
 protein coding gene Chr4:153702933-153743923 (-)
NOD/ShiLtJ ENSMUSG00190003872
 protein coding gene Chr4:143070504-143111531 (-)
NZO/HlLtJ ENSMUSG00225023648
 protein coding gene Chr4:157698088-157739110 (-)
PWK/PhJ ENSLUMG00010025022
 protein coding gene Chr4:142257625-142298717 (-)
SPRET/EiJ ENSMSPG00010022988
 protein coding gene Chr4:144154321-144230573 (-)
WSB/EiJ ENSIUOG00005044822
 protein coding gene Chr4:141242142-141283182 (-)



Homology
more
  • Human Ortholog
    PER3, period circadian regulator 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PER3, period circadian regulator 3
  • Synonyms
    FASPS3, GIG13
  • Links
    NCBI Gene ID: 8863
    UniProt: P56645

  • Chr Location
    1p36.23; chr1:7784291-7845181 (+)  GRCh38
Human Diseases
more
  • Diseases
    3 with human PER3 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 2 genetic backgrounds
    3 phenotypes from multigenic genotypes
    40 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted null mutation exhibit a shorter circadian cycle length.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    42
  • GO References
    15
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    654
  • Tissues
    56
  • cDNA Data
    46
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028957 Ensembl Gene Model | MGI Sequence Detail 41014 C57BL/6J ±  kb
transcript ENSMUST00000103204 Ensembl | MGI Sequence Detail 5999 Not Applicable  
polypeptide ENSMUSP00000099493 Ensembl | MGI Sequence Detail 1113 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 50
    cDNA 48
    Primer pair 1
    Other 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:1919967
References
more
  • Summaries
    All 105
    Developmental Gene Expression 5
    Gene Ontology 15
    Phenotypes 40
  • Earliest
    J:44820 Albrecht U, et al., A differential response of two putative mammalian circadian regulators, mper1 and mper2, to light. Cell. 1997 Dec 26;91(7):1055-64
  • Latest
    J:372079 Taufique SKT, et al., A novel circadian behavior rhythm in arrhythmic Period triple knockout mice revealed by constant light exposure. iScience. 2025 Sep 19;28(9):113292
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory