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Emp3 Gene Detail
Summary
  • Symbol
    Emp3
  • Name
    epithelial membrane protein 3
  • Synonyms
    H-4, H4, HNMP-1, MI-35, Ymp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098729
    NCBI Gene: 13732
  • Alliance
    genome feature page
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:45567447-45570828 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 29.60 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    153 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098729
 protein coding gene Chr7:45567447-45570850 (-)
129S1/SvImJ ENSMUSG00200030558
 protein coding gene Chr7:33170624-33174005 (-)
A/J ENSMUSG00195043869
 protein coding gene Chr7:37198266-37201667 (-)
AKR/J ENSMUSG00220008733
 protein coding gene Chr7:31496658-31500039 (-)
BALB/cJ ENSMUSG00180033060
 protein coding gene Chr7:34073675-34077076 (-)
C3H/HeJ ENSMUSG00175027355
 protein coding gene Chr7:34606554-34609935 (-)
C57BL/6NJ ENSMUSG00215040982
 protein coding gene Chr7:33860341-33863722 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029752
 protein coding gene Chr7:47867004-47870261 (-)
CAST/EiJ ENSTCUG00005045794
 protein coding gene Chr7:37604320-37607700 (-)
CBA/J ENSMUSG00210038726
 protein coding gene Chr7:34971304-34974685 (-)
DBA/2J ENSMUSG00185037658
 protein coding gene Chr7:38853346-38856727 (-)
FVB/NJ ENSMUSG00205035317
 protein coding gene Chr7:34515867-34519248 (-)
JF1/MsJ ENSUMUG00000043180
 protein coding gene Chr7:43333103-43336484 (-)
LP/J ENSMUSG00230051264
 protein coding gene Chr7:44287666-44291065 (-)
NOD/ShiLtJ ENSMUSG00190048975
 protein coding gene Chr7:34843566-34846947 (-)
NZO/HlLtJ ENSMUSG00225013491
 protein coding gene Chr7:42486845-42490245 (-)
PWK/PhJ ENSLUMG00010047047
 protein coding gene Chr7:33805859-33809252 (-)
SPRET/EiJ ENSMSPG00010033713
 protein coding gene Chr7:33572028-33575383 (-)
WSB/EiJ ENSIUOG00005020496
 protein coding gene Chr7:35391510-35394909 (-)



Homology
more
  • Human Ortholog
    EMP3, epithelial membrane protein 3 (MAM blood group)
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EMP3, epithelial membrane protein 3 (MAM blood group)
  • Synonyms
    YMP
  • Links
    NCBI Gene ID: 2014
    UniProt: P54852

  • Chr Location
    19q13.33; chr19:48321310-48330560 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    928
  • Tissues
    67
  • cDNA Data
    76
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040212 Ensembl Gene Model | MGI Sequence Detail 3382 C57BL/6J ±  kb
transcript ENSMUST00000038876 Ensembl | MGI Sequence Detail 736 Not Applicable  
polypeptide ENSMUSP00000037289 Ensembl | MGI Sequence Detail 163 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 78
    Genomic 1
    cDNA 76
    Other 1
    Antibodies 1

    Microarray probesets 4
References
more
  • Summaries
    All 38
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:37229 Ben-Porath I, et al., Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins. Gene. 1996 Dec 12;183(1-2):69-75
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory