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Tubb2a Gene Detail
Summary
  • Symbol
    Tubb2a
  • Name
    tubulin, beta 2A class IIA
  • Feature Type
    protein coding gene
  • IDs
    MGI:107861
    NCBI Gene: 22151
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:34258261-34261991 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 14.03 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    164 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107861
 protein coding gene Chr13:34258257-34261991 (-)
129S1/SvImJ ENSMUSG00200012032
 protein coding gene Chr13:31454073-31457806 (-)
A/J ENSMUSG00195030540
 protein coding gene Chr13:30543566-30547302 (-)
AKR/J ENSMUSG00220027072
 protein coding gene Chr13:30332875-30336610 (-)
BALB/cJ ENSMUSG00180007786
 protein coding gene Chr13:30843703-30847438 (-)
C3H/HeJ ENSMUSG00175013025
 protein coding gene Chr13:30796653-30800388 (-)
C57BL/6NJ ENSMUSG00215008768
 protein coding gene Chr13:30977621-30981353 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018418
 protein coding gene Chr13:29551290-29555102 (-)
CAST/EiJ ENSTCUG00005032007
 protein coding gene Chr13:30882551-30886319 (-)
CBA/J ENSMUSG00210011127
 protein coding gene Chr13:30809438-30813174 (-)
DBA/2J ENSMUSG00185030448
 protein coding gene Chr13:31628582-31632318 (-)
FVB/NJ ENSMUSG00205023718
 protein coding gene Chr13:30510030-30513763 (-)
JF1/MsJ ENSUMUG00000026806
 protein coding gene Chr13:31226982-31230731 (-)
LP/J ENSMUSG00230012942
 protein coding gene Chr13:40953019-40956754 (-)
NOD/ShiLtJ ENSMUSG00190011094
 protein coding gene Chr13:31034646-31038379 (-)
NZO/HlLtJ ENSMUSG00225034366
 protein coding gene Chr13:34768807-34772540 (-)
PWK/PhJ ENSLUMG00010027522
 protein coding gene Chr13:30065506-30069261 (-)
SPRET/EiJ ENSMSPG00010022631
 protein coding gene Chr13:29937755-29941485 (-)
WSB/EiJ ENSIUOG00005028015
 protein coding gene Chr13:30206098-30209832 (-)



Homology
more
  • Human Ortholog
    TUBB2A, tubulin beta 2A class IIa
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TUBB2A, tubulin beta 2A class IIa
  • Synonyms
    CDCBM5, TUBB, TUBB2
  • Links
    NCBI Gene ID: 7280
    UniProt: Q13885

  • Chr Location
    6p25.2; chr6:3153497-3157544 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human TUBB2A associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 3 alleles in 2 genetic backgrounds
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    30
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    726
  • Tissues
    66
  • cDNA Data
    182
  • Literature Summary
    15
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 22151 NCBI Gene Model | MGI Sequence Detail 3731 C57BL/6J ±  kb
    transcript NM_009450 RefSeq | MGI Sequence Detail 1638 ZRU/MplStud  
    polypeptide Q7TMM9 UniProt | EBI | MGI Sequence Detail 445 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 187
      cDNA 183
      Primer pair 4

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-36438
    References
    more
    • Summaries
      All 65
      Developmental Gene Expression 15
      Gene Ontology 6
      Phenotypes 16
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory