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Aup1 Gene Detail
Summary
  • Symbol
    Aup1
  • Name
    ancient ubiquitous protein 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:107789
    NCBI Gene: 11993
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:83031483-83034663 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 35.94 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    90 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107789
 protein coding gene Chr6:83031483-83034789 (+)
129S1/SvImJ ENSMUSG00200012175
 protein coding gene Chr6:80000860-80004147 (+)
A/J ENSMUSG00195011863
 protein coding gene Chr6:79677580-79680867 (+)
AKR/J ENSMUSG00220001867
 protein coding gene Chr6:78621019-78624306 (+)
BALB/cJ ENSMUSG00180008918
 protein coding gene Chr6:80053586-80056873 (+)
C3H/HeJ ENSMUSG00175033253
 protein coding gene Chr6:97353144-97356431 (-)
C57BL/6NJ ENSMUSG00215007925
 protein coding gene Chr6:80051093-80054380 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028537
 protein coding gene Chr6:79203543-79206829 (+)
CAST/EiJ ENSTCUG00005008102
 protein coding gene Chr6:80063936-80067220 (+)
CBA/J ENSMUSG00210010413
 protein coding gene Chr6:79869487-79872774 (+)
DBA/2J ENSMUSG00185000861
 protein coding gene Chr6:80416526-80419813 (+)
FVB/NJ ENSMUSG00205019269
 protein coding gene Chr6:79095285-79098572 (+)
JF1/MsJ ENSUMUG00000020286
 protein coding gene Chr6:79469644-79472928 (+)
LP/J ENSMUSG00230050316
 protein coding gene Chr6:81558115-81561402 (+)
NOD/ShiLtJ ENSMUSG00190001553
 protein coding gene Chr6:79498454-79501741 (+)
NZO/HlLtJ ENSMUSG00225016395
 protein coding gene Chr6:83466265-83469549 (+)
PWK/PhJ ENSLUMG00010005781
 protein coding gene Chr6:78820473-78823760 (+)
SPRET/EiJ ENSMSPG00010035677
 protein coding gene Chr6:80974329-80977611 (+)
WSB/EiJ ENSIUOG00005017424
 protein coding gene Chr6:80436211-80439498 (+)



Homology
more
  • Human Ortholog
    AUP1, AUP1 lipid droplet regulating VLDL assembly factor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AUP1, AUP1 lipid droplet regulating VLDL assembly factor
  • Links
    NCBI Gene ID: 550
    UniProt: Q9Y679

  • Chr Location
    2p13.1; chr2:74526636-74529788 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    40
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    638
  • Tissues
    28
  • cDNA Data
    162
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 11993 NCBI Gene Model | MGI Sequence Detail 3181 C57BL/6J ±  kb
transcript NR_125891 RefSeq | MGI Sequence Detail 1721 ZRU/MplStud  
polypeptide P70295 UniProt | EBI | MGI Sequence Detail 410 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 164
    Genomic 2
    cDNA 162

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-36366, MGI:2141369
References
more
  • Summaries
    All 42
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 12
  • Earliest
    J:35452 Jang W, et al., Aup1, a novel gene on mouse chromosome 6 and human chromosome 2p13. Genomics. 1996 Sep 1;36(2):366-8
  • Latest
    J:386463 Rias E, et al., Protocol for isolation of total RNA from mouse whole cochlea using organic solvents. STAR Protoc. 2026 Mar 20;7(1):104376
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory