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Csn3 Gene Detail
Summary
  • Symbol
    Csn3
  • Name
    casein kappa
  • Synonyms
    CSN10, Csnk
Location &
Maps
more
  • Sequence Map
    Chr5:88073438-88080409 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 43.56 cM
  • Mapping Data
    9 experiments
Strain
Comparison
more
  • SNPs within 2kb
    283 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107461
 protein coding gene Chr5:88073438-88080524 (+)
129S1/SvImJ ENSMUSG00200008381
 protein coding gene Chr5:83804811-83811907 (+)
A/J ENSMUSG00195024065
 protein coding gene Chr5:82975067-82982154 (+)
AKR/J ENSMUSG00220010871
 protein coding gene Chr5:83115142-83122224 (+)
BALB/cJ ENSMUSG00180022354
 protein coding gene Chr5:82807736-82814826 (+)
C3H/HeJ ENSMUSG00175036670
 protein coding gene Chr5:84882906-84889994 (+)
C57BL/6NJ ENSMUSG00215029716
 protein coding gene Chr5:83668106-83675192 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027364
 protein coding gene Chr5:80871624-80878652 (+)
CAST/EiJ ENSTCUG00005037019
 protein coding gene Chr5:82522902-82530171 (+)
CBA/J ENSMUSG00210005685
 protein coding gene Chr5:83698164-83705248 (+)
DBA/2J ENSMUSG00185039261
 protein coding gene Chr5:85617400-85624485 (+)
FVB/NJ ENSMUSG00205016909
 protein coding gene Chr5:82521640-82528720 (+)
JF1/MsJ ENSUMUG00000000900
 protein coding gene Chr5:90078566-90086034 (+)
LP/J ENSMUSG00230001407
 protein coding gene Chr5:90334794-90341880 (+)
NOD/ShiLtJ ENSMUSG00190038186
 protein coding gene Chr5:82559472-82566558 (+)
NZO/HlLtJ ENSMUSG00225007783
 protein coding gene Chr5:95364104-95371169 (+)
PWK/PhJ ENSLUMG00010024401
 protein coding gene Chr5:82587910-82595339 (+)
SPRET/EiJ ENSMSPG00010029011
 protein coding gene Chr5:84877432-84882654 (+)
WSB/EiJ ENSIUOG00005025162
 protein coding gene Chr5:85517552-85524935 (+)



Homology
more
  • Human Ortholog
    CSN3, casein kappa
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CSN3, casein kappa
  • Synonyms
    CNS10, CSN10, CSNK, KCA
  • Links
    NCBI Gene ID: 1448
    UniProt: P07498

  • Chr Location
    4q13.3; chr4:70238381-70251474 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display lactation failure and abnormal milk composition, but are fertile.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    638
  • Tissues
    27
  • cDNA Data
    761
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12994 NCBI Gene Model | MGI Sequence Detail 6972 C57BL/6J ±  kb
    transcript NM_007786 RefSeq | MGI Sequence Detail 1651 ZRU/MplStud  
    polypeptide P06796 UniProt | EBI | MGI Sequence Detail 181 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 770
      Genomic 6
      cDNA 763
      Other 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-35932, MGI:2141168
    References
    more
    • Summaries
      All 50
      Developmental Gene Expression 2
      Gene Ontology 6
      Phenotypes 13
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:349397 Gruper Y, et al., Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease. Nature. 2023 Dec;624(7992):653-662
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory