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Tgoln1 Gene Detail
Summary
  • Symbol
    Tgoln1
  • Name
    trans-golgi network protein
  • Synonyms
    D6Ertd384e, TGN38, TGN38A, Ttgn1
  • Feature Type
    protein coding gene
  • IDs
    MGI:105080
    NCBI Gene: 22134
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:72585415-72593983 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 32.27 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    255 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105080
 protein coding gene Chr6:72585403-72593983 (-)
129S1/SvImJ ENSMUSG00200010847
 protein coding gene Chr6:69489489-69498058 (-)
A/J ENSMUSG00195042025
 protein coding gene Chr6:69251726-69260295 (-)
AKR/J ENSMUSG00220040584
 protein coding gene Chr6:68231613-68240185 (-)
BALB/cJ ENSMUSG00180034126
 protein coding gene Chr6:69606707-69615275 (-)
C3H/HeJ ENSMUSG00175011253
 protein coding gene Chr6:107805235-107813411 (+)
C57BL/6NJ ENSMUSG00215042038
 protein coding gene Chr6:69579446-69588015 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028510
 protein coding gene Chr6:69476900-69484392 (-)
CAST/EiJ ENSTCUG00005030821
 protein coding gene Chr6:69738228-69746389 (-)
CBA/J ENSMUSG00210036327
 protein coding gene Chr6:69437283-69445458 (-)
DBA/2J ENSMUSG00185040359
 protein coding gene Chr6:69997418-70005591 (-)
FVB/NJ ENSMUSG00205029362
 protein coding gene Chr6:68702220-68710788 (-)
JF1/MsJ ENSUMUG00000035118
 protein coding gene Chr6:69048083-69056210 (-)
LP/J ENSMUSG00230006637
 protein coding gene Chr6:71084465-71093033 (-)
NOD/ShiLtJ ENSMUSG00190033222
 protein coding gene Chr6:68978313-68986438 (-)
NZO/HlLtJ ENSMUSG00225006707
 protein coding gene Chr6:73058369-73066936 (-)
PWK/PhJ ENSLUMG00010018915
 protein coding gene Chr6:68457329-68465448 (-)
SPRET/EiJ ENSMSPG00010024255
 protein coding gene Chr6:70289843-70294679 (-)
WSB/EiJ ENSIUOG00005022290
 protein coding gene Chr6:69986561-69994733 (-)



Homology
more
  • Human Ortholog
    TGOLN2, trans-golgi network protein 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TGOLN2, trans-golgi network protein 2
  • Synonyms
    hTGN46, hTGN48, hTGN51, TGN38, TGN46, TGN48, TGN51, TTGN2
  • Links
    NCBI Gene ID: 10618
    UniProt: O43493

  • Chr Location
    2p11.2; chr2:85318027-85328251 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    607
  • Tissues
    3
  • cDNA Data
    18
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000056429 Ensembl Gene Model | MGI Sequence Detail 8569 C57BL/6J ±  kb
    transcript ENSMUST00000070524 Ensembl | MGI Sequence Detail 5013 Not Applicable  
    polypeptide ENSMUSP00000068487 Ensembl | MGI Sequence Detail 353 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 20
      cDNA 19
      Primer pair 1
      Antibodies 3

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-32120, MGI:1196440, MGI:2141549
    References
    more
    • Summaries
      All 60
      Developmental Gene Expression 6
      Gene Ontology 12
      Phenotypes 11
    • Earliest
      J:26092 Kasai K, et al., Strain-specific presence of two TGN38 isoforms and absence of TGN41 in mouse. J Biol Chem. 1995 Jun 16;270(24):14471-6
    • Latest
      J:386463 Rias E, et al., Protocol for isolation of total RNA from mouse whole cochlea using organic solvents. STAR Protoc. 2026 Mar 20;7(1):104376
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory