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Mtcp1 Gene Detail
Summary
  • Symbol
    Mtcp1
  • Name
    mature T cell proliferation 1
Location &
Maps
more
  • Sequence Map
    ChrX:74454048-74460190 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 38.22 cM
Strain
Comparison
more
  • SNPs within 2kb
    184 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102699
 protein coding gene ChrX:74454048-74460194 (-)
129S1/SvImJ ENSMUSG00200040939
 protein coding gene ChrX:56470347-56476498 (-)
A/J ENSMUSG00195031188
 protein coding gene ChrX:60194951-60201093 (-)
AKR/J ENSMUSG00220045444
 protein coding gene ChrX:55349283-55355431 (-)
BALB/cJ ENSMUSG00180049267
 protein coding gene ChrX:56769657-56775797 (-)
C3H/HeJ ENSMUSG00175034279
 protein coding gene ChrX:60360156-60366300 (-)
C57BL/6NJ ENSMUSG00215038065
 protein coding gene ChrX:56855640-56861786 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033197
 protein coding gene ChrX:70986175-70992224 (-)
CAST/EiJ ENSTCUG00005038626
 protein coding gene ChrX:58238617-58244771 (-)
CBA/J ENSMUSG00210042918
 protein coding gene ChrX:57039952-57046094 (-)
DBA/2J ENSMUSG00185031943
 protein coding gene ChrX:69461694-69467838 (-)
FVB/NJ ENSMUSG00205036014
 protein coding gene ChrX:56327402-56333546 (-)
JF1/MsJ ENSUMUG00000042228
 protein coding gene ChrX:90297160-90303308 (-)
LP/J ENSMUSG00230035456
 protein coding gene ChrX:76028921-76035072 (-)
NOD/ShiLtJ ENSMUSG00190038662
 protein coding gene ChrX:56279764-56285906 (-)
NZO/HlLtJ ENSMUSG00225047578
 protein coding gene ChrX:81245015-81251161 (-)
PWK/PhJ ENSLUMG00010042555
 protein coding gene ChrX:55918305-55924430 (-)
SPRET/EiJ ENSMSPG00010028345
 protein coding gene ChrX:59310667-59316072 (-)
WSB/EiJ ENSIUOG00005045051
 protein coding gene ChrX:57038383-57044532 (-)



Homology
more
  • Human Ortholog
    MTCP1, mature T cell proliferation 1
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MTCP1, mature T cell proliferation 1
  • Synonyms
    P13MTCP1, p8MTCP1, TCL1C
  • Links
    NCBI Gene ID: 4515
    UniProt: P56278

  • Chr Location
    Xq28; chrX:155064034-155147937 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    655
  • Tissues
    51
  • cDNA Data
    23
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 17763 NCBI Gene Model | MGI Sequence Detail 6143 C57BL/6J ±  kb
transcript NM_001039373 RefSeq | MGI Sequence Detail 1635 C57BL/6  
polypeptide Q60945 UniProt | EBI | MGI Sequence Detail 107 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    cDNA 24
    Primer pair 2

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-19603
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:21838 Soulier J, et al., The MTCP-1/c6.1B gene encodes for a cytoplasmic 8 kD protein overexpressed in T cell leukemia bearing a t(X;14) translocation. Oncogene. 1994 Dec;9(12):3565-70
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory